AIMC Topic: Machine Learning

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Toward a unified framework for interpreting machine-learning models in neuroimaging.

Nature protocols
Machine learning is a powerful tool for creating computational models relating brain function to behavior, and its use is becoming widespread in neuroscience. However, these models are complex and often hard to interpret, making it difficult to evalu...

A Review on Applications of Computational Methods in Drug Screening and Design.

Molecules (Basel, Switzerland)
Drug development is one of the most significant processes in the pharmaceutical industry. Various computational methods have dramatically reduced the time and cost of drug discovery. In this review, we firstly discussed roles of multiscale biomolecul...

AI-Driven Tools for Coronavirus Outbreak: Need of Active Learning and Cross-Population Train/Test Models on Multitudinal/Multimodal Data.

Journal of medical systems
The novel coronavirus (COVID-19) outbreak, which was identified in late 2019, requires special attention because of its future epidemics and possible global threats. Beside clinical procedures and treatments, since Artificial Intelligence (AI) promis...

Identifying predictive features of autism spectrum disorders in a clinical sample of adolescents and adults using machine learning.

Scientific reports
Diagnosing autism spectrum disorders (ASD) is a complicated, time-consuming process which is particularly challenging in older individuals. One of the most widely used behavioral diagnostic tools is the Autism Diagnostic Observation Schedule (ADOS). ...

SAEROF: an ensemble approach for large-scale drug-disease association prediction by incorporating rotation forest and sparse autoencoder deep neural network.

Scientific reports
Drug-disease association is an important piece of information which participates in all stages of drug repositioning. Although the number of drug-disease associations identified by high-throughput technologies is increasing, the experimental methods ...

Improving the binding affinity estimations of protein-ligand complexes using machine-learning facilitated force field method.

Journal of computer-aided molecular design
Scoring functions are routinely deployed in structure-based drug design to quantify the potential for protein-ligand (PL) complex formation. Here, we present a new scoring function Bappl+ that is designed to predict the binding affinities of non-meta...

Artificial intelligence and machine learning in respiratory medicine.

Expert review of respiratory medicine
: The application of artificial intelligence (AI) and machine learning (ML) in medicine and in particular in respiratory medicine is an increasingly relevant topic.: We aimed to identify and describe the studies published on the use of AI and ML in t...

Application of a Deep Machine Learning Model for Automatic Measurement of EZ Width in SD-OCT Images of RP.

Translational vision science & technology
PURPOSE: We applied a deep convolutional neural network model for automatic identification of ellipsoid zone (EZ) in spectral domain optical coherence tomography B-scans of retinitis pigmentosa (RP).