Machine learning is a powerful tool for creating computational models relating brain function to behavior, and its use is becoming widespread in neuroscience. However, these models are complex and often hard to interpret, making it difficult to evalu...
Circulation. Arrhythmia and electrophysiology
Mar 18, 2020
BACKGROUND: Transition zones between healthy myocardium and scar form a spatially complex substrate that may give rise to reentrant ventricular arrhythmias (VAs). We sought to assess the utility of a novel machine learning approach for quantifying 3-...
Drug development is one of the most significant processes in the pharmaceutical industry. Various computational methods have dramatically reduced the time and cost of drug discovery. In this review, we firstly discussed roles of multiscale biomolecul...
The novel coronavirus (COVID-19) outbreak, which was identified in late 2019, requires special attention because of its future epidemics and possible global threats. Beside clinical procedures and treatments, since Artificial Intelligence (AI) promis...
Diagnosing autism spectrum disorders (ASD) is a complicated, time-consuming process which is particularly challenging in older individuals. One of the most widely used behavioral diagnostic tools is the Autism Diagnostic Observation Schedule (ADOS). ...
Drug-disease association is an important piece of information which participates in all stages of drug repositioning. Although the number of drug-disease associations identified by high-throughput technologies is increasing, the experimental methods ...
Journal of computer-aided molecular design
Mar 17, 2020
Scoring functions are routinely deployed in structure-based drug design to quantify the potential for protein-ligand (PL) complex formation. Here, we present a new scoring function Bappl+ that is designed to predict the binding affinities of non-meta...
Expert review of respiratory medicine
Mar 17, 2020
: The application of artificial intelligence (AI) and machine learning (ML) in medicine and in particular in respiratory medicine is an increasingly relevant topic.: We aimed to identify and describe the studies published on the use of AI and ML in t...
Translational vision science & technology
Mar 17, 2020
PURPOSE: We applied a deep convolutional neural network model for automatic identification of ellipsoid zone (EZ) in spectral domain optical coherence tomography B-scans of retinitis pigmentosa (RP).
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