AIMC Topic: Machine Learning

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Development of a CNN for Adult Brain Tumour Characterisation: Implications and Future Directions for Transfer Learning.

Studies in health technology and informatics
Brain tumours are the most commonly occurring solid tumours in children, albeit with lower incidence rates compared to adults. However, their inherent heterogeneity, ethical considerations regarding paediatric patients, and difficulty in long-term fo...

Harnessing the Power of Machine Learning and Electronic Health Records to Support Child Abuse and Neglect Identification in Emergency Department Settings.

Studies in health technology and informatics
Emergency departments (EDs) are pivotal in detecting child abuse and neglect, but this task is often complex. Our study developed a machine learning model using structured and unstructured electronic health record (EHR) data to predict when children ...

Temporal Characterization and Visualization of Revolving Therapy-Events in Lung Cancer Patients.

Studies in health technology and informatics
This paper presents a comprehensive workflow for integrating revolving events into the transitive sequential pattern mining (tSPM+) algorithm and Machine Learning for Health Outcomes (MLHO) framework, emphasizing best practices and pitfalls in its ap...

From Data Mining of Public Sources to Clinical Decision Support in Personalized Medicine.

Studies in health technology and informatics
Personalized medicine enables precise tumor treatment for a patient's molecular genetic profile. To devise optimal targeted treatment plans for patients in a molecular tumor board, physicians must consider alterations on gene- and proteins levels but...

Predicting Patient No-Shows: Situated Machine Learning with Imperfect Data.

Studies in health technology and informatics
Patients who do not show up for scheduled appointments are a considerable cost and concern in healthcare. In this study, we predict patient no-shows for outpatient surgery at the endoscopy ward of a hospital in Denmark. The predictions are made by tr...

Fracture risk prediction in postmenopausal women with traditional and machine learning models in a nationwide, prospective cohort study in Switzerland with validation in the UK Biobank.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Fracture prediction is essential in managing patients with osteoporosis and is an integral component of many fracture prevention guidelines. We aimed to identify the most relevant clinical fracture risk factors in contemporary populations by training...

Machine learning-based analysis identifies and validates serum exosomal proteomic signatures for the diagnosis of colorectal cancer.

Cell reports. Medicine
The potential of serum extracellular vesicles (EVs) as non-invasive biomarkers for diagnosing colorectal cancer (CRC) remains elusive. We employed an in-depth 4D-DIA proteomics and machine learning (ML) pipeline to identify key proteins, PF4 and AACT...

Effect of Human Head Shape on the Risk of Traumatic Brain Injury: A Gaussian Process Regression-Based Machine Learning Approach.

Military medicine
INTRODUCTION: Computational head injury models are promising tools for understanding and predicting traumatic brain injuries. However, most available head injury models are "average" models that employ a single set of head geometry (e.g., 50th-percen...

Machine learning models for differential diagnosing HER2-low breast cancer: A radiomics approach.

Medicine
To develop machine learning models based on preoperative dynamic enhanced magnetic resonance imaging (DCE-MRI) radiomics and to explore their potential prognostic value in the differential diagnosis of human epidermal growth factor receptor 2 (HER2)-...

CT radiomics-based machine learning model for differentiating between enchondroma and low-grade chondrosarcoma.

Medicine
It may be difficult to distinguish between enchondroma and low-grade malignant cartilage tumors (grade 1) radiologically. This study aimed to construct machine learning models using 3D computed tomography (CT)-based radiomics analysis to differentiat...