Mitochondrial dysfunction plays a pivotal role in the pathogenesis of chronic obstructive pulmonary disease (COPD). This study combines bioinformatics analysis with machine learning to elucidate potential key mitochondrial-related genes associated wi...
Small Ubiquitin-like MOdifier-mediated modification (SUMOylation) is associated with sepsis; however, its molecular mechanism remains unclear. Herein, hub genes and regulatory mechanisms in sepsis was investigated. The GSE65682 and GSE95233 datasets ...
Bone marrow (BM) plays a crucial role in the hematopoietic process, producing all of the body's blood cells and maintaining the overall immune and health system. Red and yellow BM are the two various kinds of BM. A comprehensive identification of the...
Young adults with childhood sexual abuse (CSA) are an especially vulnerable group to suicide. Suicide encompasses different phases, but for CSA survivors the salient factors precipitating suicide are rarely studied. In this study, from a progressive ...
Artificial intelligence (AI) has revolutionized various biomedical fields, particularly immunology, by enhancing vaccine development, immunotherapies, and allergy treatments. AI helps identify potential vaccine candidates and predict how the body rea...
Environmental monitoring and assessment
Apr 24, 2025
Urbanization and industrialization have led to widespread soil heavy metals contamination, posing significant risks to ecosystems and human health. Conventional methods for mapping heavy metal distribution, which rely on soil sampling followed by che...
BACKGROUND: Isolated Impaired Glucose Tolerance (I-IGT) represents a specific prediabetic state that typically requires a standardized oral glucose tolerance test (OGTT) for diagnosis. This study aims to predict glucose tolerance status in Chinese Ha...
Experimental biology and medicine (Maywood, N.J.)
Apr 24, 2025
Attention deficit/hyperactivity disorder is a common neuropsychiatric disorder that affects around 5%-7% of children worldwide. Artificial intelligence provides advanced models and algorithms for better diagnosis, prediction and classification of att...
PURPOSE: Despite the development of diverse treatment options, there has been an increase in mortality rates for laryngeal squamous cell carcinoma (LSCC). Our research employed survival analysis and machine learning (ML) techniques to evaluate the im...
Riboswitches are a class of noncoding RNA structures that interact with target ligands to cause a conformational change that can then execute some regulatory purpose within the cell. Riboswitches are ubiquitous and well characterized in bacteria and ...
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