AIMC Topic: Machine Learning

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Optimizing predictive features using machine learning for early miscarriage risk following single vitrified-warmed blastocyst transfer.

Frontiers in endocrinology
RESEARCH QUESTION: Can machine learning models accurately predict the risk of early miscarriage following single vitrified-warmed blastocyst transfer (SVBT)?

Heavy metal biomarkers and their impact on hearing loss risk: a machine learning framework analysis.

Frontiers in public health
BACKGROUND: Exposure to heavy metals has been implicated in adverse auditory health outcomes, yet the precise relationships between heavy metal biomarkers and hearing status remain underexplored. This study leverages a machine learning framework to i...

Constructing a screening model to identify patients at high risk of hospital-acquired influenza on admission to hospital.

Frontiers in public health
OBJECTIVE: To develop a machine learning (ML)-based admission screening model for hospital-acquired (HA) influenza using routinely available data to support early clinical intervention.

Machine learning model for age related macular degeneration based on pesticides: the National Health and Nutrition Examination Survey 2007-2008.

Frontiers in public health
Age-related macular degeneration (AMD) is the most common cause of irreversible deterioration of vision in older adults. Previous studies have found that exposure to pesticides can lead to a worsening of AMD. In this paper, information on pesticide e...

Artificial intelligence-assisted RNA-binding protein signature for prognostic stratification and therapeutic guidance in breast cancer.

Frontiers in immunology
BACKGROUND: Breast cancer is the most common malignancy in women globally, with significant heterogeneity affecting prognosis and treatment. RNA-binding proteins play vital roles in tumor progression, yet their prognostic potential remains unclear. T...

Quantitative MRI radiomics approach for evaluating muscular alteration in Crohn disease: development of a machine learning-nomogram composite diagnostic tool.

Abdominal radiology (New York)
BACKGROUND: Emerging evidence underscores smooth muscle hyperplasia and hypertrophy, rather than fibrosis, as the defining characteristics of fibrostenotic lesions in Crohn disease (CD). However, non-invasive methods for quantifying these muscular ch...

Integration of machine learning and experimental validation reveals new lipid-lowering drug candidates.

Acta pharmacologica Sinica
Hyperlipidemia, a major risk factor for cardiovascular diseases, is associated with limitations in clinical lipid-lowering medications. Drug repurposing strategies expedite the research process and mitigate development costs, offering an innovative a...

Prediction and Evaluation of Coronavirus and Human Protein-Protein Interactions Integrating Five Different Computational Methods.

Proteins
The high lethality and infectiousness of coronaviruses, particularly SARS-Cov-2, pose a significant threat to human society. Understanding coronaviruses, especially the interactions between these viruses and humans, is crucial for mitigating the coro...

A Multi-Omics-Based Prognostic Model for Elderly Breast Cancer by Machine Learning: Insights From Hypoxia and Immunity of Tumor Microenvironment.

Clinical breast cancer
INTRODUCTION: Older adult breast cancer (OABC) patients (≥ 65 years) frequently experience poorer prognoses compared to younger adults, attributed to complex tumor biology and age-related factors. The present study employs a multiomics approach combi...

Identification and Validation of Ferritinophagy-Related Biomarkers in Periodontitis.

International dental journal
OBJECTIVE: While ferritinophagy is believed to play a significant role in the development of periodontitis, the exact mechanisms remain unclear. This study aimed to investigate the biomarkers associated with ferritinophagy in periodontitis using tran...