AIMC Topic: Machine Learning

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Unmasking Neuroendocrine Prostate Cancer with a Machine Learning-Driven Seven-Gene Stemness Signature That Predicts Progression.

International journal of molecular sciences
Prostate cancer (PCa) poses a significant global health challenge, particularly due to its progression into aggressive forms like neuroendocrine prostate cancer (NEPC). This study developed and validated a stemness-associated gene signature using adv...

Development and validation of a cardiovascular risk prediction model for Sri Lankans using machine learning.

PloS one
INTRODUCTION AND OBJECTIVES: Sri Lankans do not have a specific cardiovascular (CV) risk prediction model and therefore, World Health Organization(WHO) risk charts developed for the Southeast Asia Region are being used. We aimed to develop a CV risk ...

Transfer Learning With Active Sampling for Rapid Training and Calibration in BCI-P300 Across Health States and Multi-Centre Data.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Machine learning and deep learning advancements have boosted Brain-Computer Interface (BCI) performance, but their wide-scale applicability is limited due to factors like individual health, hardware variations, and cultural differences affecting neur...

Reproducibility and interpretability in radiomics: a critical assessment.

Diagnostic and interventional radiology (Ankara, Turkey)
Radiomics aims to improve clinical decision making through the use of radiological imaging. However, the field is challenged by reproducibility issues due to variability in imaging and subsequent statistical analysis, which particularly affects the i...

Medical diagnosis based on artificial intelligence and decision support system in the management of health development.

Journal of evaluation in clinical practice
BACKGROUND: Medical diagnosis plays a critical role in our daily lives. Every day, over 10 billion cases of both mental and physical health disorders are diagnosed and reported worldwide. To diagnose these disorders, medical practitioners and health ...

Enhancing endometrial cancer detection: Blood serum intrinsic fluorescence data processing and machine learning application.

Talanta
Endometrial cancer (EC) is the most prevalent cancer within the female reproductive system in developed countries. Despite its high incidence, there is currently no established laboratory screening test for EC, making early detection challenging. Thi...

Decoding wheat contamination through self-assembled whole-cell biosensor combined with linear and non-linear machine learning algorithms.

Biosensors & bioelectronics
The contamination of mycotoxins is a serious problem around the world. It has detrimental effects on human beings and leads to tremendous economic loss. It is essential to develop a rapid and non-destructive method for contamination recognition parti...

Enhancing amide proton transfer imaging in ischemic stroke using a machine learning approach with partially synthetic data.

NMR in biomedicine
Amide proton transfer (APT) imaging, a technique sensitive to tissue pH, holds promise in the diagnosis of ischemic stroke. Achieving accurate and rapid APT imaging is crucial for this application. However, conventional APT quantification methods eit...

Machine learning identification of NK cell immune characteristics in hepatocellular carcinoma based on single-cell sequencing and bulk RNA sequencing.

Genes & genomics
BACKGROUND: Hepatocellular carcinoma (HCC) is a highly malignant tumor; however, its immune microenvironment and mechanisms remain elusive. Single-cell sequencing allows for the exploration of immune characteristics within tumor at the cellular level...

Advancing Anticancer Drug Discovery: Leveraging Metabolomics and Machine Learning for Mode of Action Prediction by Pattern Recognition.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
A bottleneck in the development of new anti-cancer drugs is the recognition of their mode of action (MoA). Metabolomics combined with machine learning allowed to predict MoAs of novel anti-proliferative drug candidates, focusing on human prostate can...