AIMC Topic: Machine Learning

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Combining multi-parametric MRI radiomics features with tumor abnormal protein to construct a machine learning-based predictive model for prostate cancer.

Scientific reports
This study aims to investigate the diagnostic value of integrating multi-parametric magnetic resonance imaging (mpMRI) radiomic features with tumor abnormal protein (TAP) and clinical characteristics for diagnosing prostate cancer. A cohort of 109 pa...

Developing transferable and universal IR biomarkers for intraoperative colorectal cancer diagnosis via FTIR spectroscopy.

Scientific reports
Histological staining has long been the gold standard for cancer detection, but it is limited by subjectivity and delayed results. Fourier Transform Infrared Spectroscopy (FTIR) has emerged as a promising technique, offering the advantages of objecti...

Cross modality learning of cell painting and transcriptomics data improves mechanism of action clustering and bioactivity modelling.

Scientific reports
In drug discovery, different data modalities (chemical structure, cell biology, quantum mechanics, etc.) are abundant, and their integration can help with understanding aspects of chemistry, biology, and their interactions. Within cell biology, cell ...

Employee loyalty evaluation using machine learning in technology-based small and medium-sized enterprises.

Scientific reports
Employee loyalty is a major issue of sustainable human resource management. Small and medium-sized enterprises with high technology content and strong innovation ability are the main body of innovation with great vitality and potential. Employee loya...

Unveiling diagnostic biomarkers and therapeutic targets in lung adenocarcinoma using bioinformatics and experimental validation.

Scientific reports
Lung adenocarcinoma (LUAD) is a major challenge in oncology due to its complex molecular structure and generally poor prognosis. The aim of this study was to find diagnostic markers and therapeutic targets for LUAD by integrating differential gene ex...

Identification of exosome-related genes in NSCLC via integrated bioinformatics and machine learning analysis.

Scientific reports
Exosomes are crucial in the development of non-small cell lung cancer (NSCLC), yet exosome-associated genes in NSCLC remain insufficiently explored. The present study identified 59 exosome-associated differentially expressed genes (EA-DEGs) from the ...

Improved bio-inspired with machine learning computing approach for thyroid prediction.

Scientific reports
Thyroid illness is widely recognised as a prevalent health condition that can result in a range of health disorders. Thyroid illnesses, namely hypothyroidism and hyperthyroidism, are widespread worldwide and present considerable health consequences. ...

Hybrid machine learning and physics-based model for estimating lettuce (Lactuca sativa) growth and resource consumption in aeroponic systems.

Scientific reports
As the global population is expected to reach 10.3 billion by the mid-2080s, optimizing agricultural production and resource management is crucial. Climate change and environmental degradation further complicate these challenges, impacting crop produ...

Integrating machine learning and bioinformatics approaches to identify novel diagnostic gene biomarkers for diabetic mice.

Scientific reports
Diabetes is a complex metabolic disorder, and its pathogenesis involves the interplay of genetic, environmental factors, and lifestyle choices. With the rising prevalence and increasing associated chronic complications, identifying and understanding ...

Comprehensive machine learning analysis of PANoptosis signatures in multiple myeloma identifies prognostic and immunotherapy biomarkers.

Scientific reports
PANoptosis is closely associated with tumorigenesis and therapeutic response, yet its role in multiple myeloma (MM) remains unclear. This study analyzed bulk transcriptomic and clinical data from the TCGA and GEO databases to identify seven PANoptosi...