AIMC Topic: Machine Learning

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Development and Validation of an Explainable Machine Learning Model for Predicting Myocardial Injury After Noncardiac Surgery in Two Centers in China: Retrospective Study.

JMIR aging
BACKGROUND: Myocardial injury after noncardiac surgery (MINS) is an easily overlooked complication but closely related to postoperative cardiovascular adverse outcomes; therefore, the early diagnosis and prediction are particularly important.

Identification of profiles associated with conversions between the Alzheimer's disease stages, using a machine learning approach.

Alzheimer's research & therapy
BACKGROUND: The identification of factors involved in the conversion across the different Alzheimer's disease (AD) stages is crucial to prevent or slow the disease progression. We aimed to assess the factors and their combination associated with the ...

Multi-parametric MRI-based machine learning model for prediction of pathological grade of renal injury in a rat kidney cold ischemia-reperfusion injury model.

BMC medical imaging
BACKGROUND: Renal cold ischemia-reperfusion injury (CIRI), a pathological process during kidney transplantation, may result in delayed graft function and negatively impact graft survival and function. There is a lack of an accurate and non-invasive t...

Adopting machine learning to predict ICU delirium.

Neurosurgical review
With neuropsychiatric complications recognized among COVID-19 patients translating into significant morbidity, we explore the current state-of-the-art for auto Machine Learning (ML) to predict ICU delirium among severe COVID-19 patients which has bee...

A data-centric machine learning approach to improve prediction of glioma grades using low-imbalance TCGA data.

Scientific reports
Accurate prediction and grading of gliomas play a crucial role in evaluating brain tumor progression, assessing overall prognosis, and treatment planning. In addition to neuroimaging techniques, identifying molecular biomarkers that can guide the dia...

Hybrid framework for membrane protein type prediction based on the PSSM.

Scientific reports
Membrane proteins are considered the major source of drug targets and are indispensable for drug design and disease prevention. However, traditional biomechanical experiments are costly and time-consuming; thus, many computational methods for predict...

Machine-learning-assisted high-throughput identification of potent and stable neutralizing antibodies against all four dengue virus serotypes.

Scientific reports
Several computational methods have been developed to identify neutralizing antibodies (NAbs) covering four dengue virus serotypes (DENV-1 to DENV-4); however, limitations of the dataset and the resulting performance remain. Here, we developed a new c...

Holistic evaluation of a machine learning-based timing calibration for PET detectors under varying data sparsity.

Physics in medicine and biology
Modern PET scanners offer precise TOF information, improving the SNR of the reconstructed images. Timing calibrations are performed to reduce the worsening effects of the system components and provide valuable TOF information. Traditional calibration...

Pitfalls in Developing Machine Learning Models for Predicting Cardiovascular Diseases: Challenge and Solutions.

Journal of medical Internet research
In recent years, there has been explosive development in artificial intelligence (AI), which has been widely applied in the health care field. As a typical AI technology, machine learning models have emerged with great potential in predicting cardiov...

DeepDRA: Drug repurposing using multi-omics data integration with autoencoders.

PloS one
Cancer treatment has become one of the biggest challenges in the world today. Different treatments are used against cancer; drug-based treatments have shown better results. On the other hand, designing new drugs for cancer is costly and time-consumin...