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Artificial intelligence in anesthesia: comparison of the utility of ChatGPT v/s google gemini large language models in pre-anesthetic education: content, readability and sentiment analysis.

BMC anesthesiology
BACKGROUND: Large Language Models (LLMs) such as ChatGPT and Google Gemini are increasingly explored for their potential in patient education, particularly in the perioperative setting. As text-based tools trained on extensive datasets, they can gene...

Using machine learning for detection of Parkinson's disease and mild cognitive impairment.

PloS one
BACKGROUND: Parkinson's disease is a movement disorder featuring motor symptoms and cognitive decline, which can manifest as mild cognitive impairment. The incidence of mild cognitive impairment increases with disease progression, and Parkinson's dis...

ATR-FTIR Spectroscopy of Saliva and Machine Learning as a Screening Test for Sjögren Disease.

Analytical chemistry
Sjögren's disease is often an underdiagnosed autoimmune condition that primarily affects the exocrine glands, resulting in symptoms such as dry eyes and dry mouth. Diagnostic challenges stem from nonspecific symptoms, the absence of definitive biomar...

Artificial Intelligence-Driven Discovery of Pyrazolo[1,5-]pyrimidine Derivatives as Novel Phosphodiesterase 4 Inhibitors for Treating Idiopathic Pulmonary Fibrosis.

Journal of medicinal chemistry
Phosphodiesterase 4 (PDE4) has been validated as a promising therapeutic target for idiopathic pulmonary fibrosis (IPF), a devastating interstitial lung disease lacking really effective therapeutic drugs, particularly exacerbated in the post-COVID-19...

Using Machine Learning Methods to Examine Turnover Rates in State Health Agencies.

Journal of public health management and practice : JPHMP
CONTEXT: High turnover rates in the public health workforce pose ongoing challenges to maintain essential services and institutional knowledge. Recent studies indicate that job dissatisfaction, burnout, and structural barriers have intensified follow...

Spatial profiling of HPV-stratified head and neck squamous cell carcinoma reveals distinct immune niches and microenvironmental architectures.

Journal of translational medicine
BACKGROUND: HPV status is a key determinant of prognosis and treatment response in head and neck squamous cell carcinoma (HNSCC). To investigate how HPV influences the tumor-immune-stromal landscape, we performed high-dimensional spatial profiling, i...

Perceived fatigue progression tracking during manual handling tasks using sEMG recordings.

Journal of neuroengineering and rehabilitation
Physical fatigue significantly contributes to work-related musculoskeletal disorders, highlighting the need to understand its effects during manual handling tasks for effective prevention strategies. This study examines the correlation between change...

Relationship between C-reactive protein triglyceride glucose index and cardiovascular disease risk: a cross-sectional analysis with machine learning.

BMC medical informatics and decision making
BACKGROUND: Cardiovascular disease (CVD) continues to be a leading cause of disease burden and mortality worldwide. Identifying reliable biomarkers for CVD risk assessment is essential. This study investigates the association between the C-reactive p...

Distinct immune-metabolic phenotypes underlie poor coronary collateral circulation.

Cardiovascular diabetology
BACKGROUND: Coronary collateral circulation (CCC) significantly impacts myocardial perfusion and clinical outcomes in coronary artery disease patients, yet the underlying molecular heterogeneity remains inadequately characterized.

Unveiling the burden of snakebite injuries: an EQ-5D-5 L-based evaluation of health-related quality of life.

BMC public health
BACKGROUND: Snakebite envenoming remains poorly understood in terms of long-term health-related quality of life (HRQoL), particularly in China where standardized assessments are lacking. This study is the first to comprehensively evaluate HRQoL impai...