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Metabolic reprogramming and macrophage expansion define ACPA-negative rheumatoid arthritis: insights from single-cell RNA sequencing.

Frontiers in immunology
BACKGROUND: Anti-citrullinated peptide antibodies (ACPA)-negative (ACPA-) rheumatoid arthritis (RA) presents significant diagnostic and therapeutic challenges due to the absence of specific biomarkers, underscoring the need to elucidate its distincti...

ReIU: an efficient preliminary framework for Alzheimer patients based on multi-model data.

Frontiers in public health
The rising incidence of Alzheimer's disease (AD) poses significant challenges to traditional diagnostic methods, which primarily rely on neuropsychological assessments and brain MRIs. The advent of deep learning in medical diagnosis opens new possibi...

How do neighborhood environments impact adolescent health: a comprehensive study from subjective and objective perspectives using machine learning method.

Frontiers in public health
Existing studies have established a linear relationship between urban environments and adolescent health, but the combined impacts of subjective and objective environments on multi-dimensional health status (including physical and mental health) have...

STI/HIV risk prediction model development-A novel use of public data to forecast STIs/HIV risk for men who have sex with men.

Frontiers in public health
A novel automatic framework is proposed for global sexually transmissible infections (STIs) and HIV risk prediction. Four machine learning methods, namely, Gradient Boosting Machine (GBM), Random Forest (RF), XG Boost, and Ensemble learning GBM-RF-XG...

Artificial Intelligence Assistance in Point-of-Care Ultrasound Skill Retention for Novice Users in Space Medicine Scenarios.

Wilderness & environmental medicine
IntroductionAs humanity progresses further into space, astronauts must be increasingly independent from mission control, especially in high-consequence medical scenarios. The high-utility and low-mass nature of point-of-care ultrasound (POCUS) makes ...

Malignancy risk stratification for pulmonary nodules: comparing a deep learning approach to multiparametric statistical models in different disease groups.

European radiology
OBJECTIVES: Incidentally detected pulmonary nodules present a challenge in clinical routine with demand for reliable support systems for risk classification. We aimed to evaluate the performance of the lung-cancer-prediction-convolutional-neural-netw...

Automated Cone Beam Computed Tomography Segmentation of Multiple Impacted Teeth With or Without Association to Rare Diseases: Evaluation of Four Deep Learning-Based Methods.

Orthodontics & craniofacial research
OBJECTIVE: To assess the accuracy of three commercially available and one open-source deep learning (DL) solutions for automatic tooth segmentation in cone beam computed tomography (CBCT) images of patients with multiple dental impactions.

Efficacy of a deep learning system for automatic analysis of the comprehensive spatial relationship between the mandibular third molar and inferior alveolar canal on panoramic radiographs.

Oral surgery, oral medicine, oral pathology and oral radiology
OBJECTIVE: To develop and evaluate a deep learning (DL) system for predicting the contact and relative position relationships between the mandibular third molar (M3) and inferior alveolar canal (IAC) using panoramic radiographs (PRs) for preoperative...

Radiomics and Deep Learning Model for Benign and Malignant Soft Tissue Tumors Differentiation of Extremities and Trunk.

Academic radiology
RATIONALE AND OBJECTIVES: To develop radiomics and deep learning models for differentiating malignant and benign soft tissue tumors (STTs) preoperatively based on fat saturation T2-weighted imaging (FS-T2WI) of patients.