AIMC Topic: Methotrexate
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Machine Learning to Predict Anti-Tumor Necrosis Factor Drug Responses of Rheumatoid Arthritis Patients by Integrating Clinical and Genetic Markers.
Arthritis & rheumatology (Hoboken, N.J.)
Nov 4, 2019
OBJECTIVE: Accurate prediction of treatment responses in rheumatoid arthritis (RA) patients can provide valuable information on effective drug selection. Anti-tumor necrosis factor (anti-TNF) drugs are an important second-line treatment after methotr...
Methotrexate
Adalimumab
Genetic Markers
Normal Distribution
Etanercept
Antirheumatic Agents
Outcome Assessment, Health Care
Regression Analysis
Infliximab
Predictive Value of Tests
Polymorphism, Single Nucleotide
Treatment Outcome
Arthritis, Rheumatoid
Humans
Certolizumab Pegol
Male
Reproducibility of Results
Severity of Illness Index
Middle Aged
Tumor Necrosis Factor-alpha
Female
Machine Learning
Dual-mode nanosensor for sensitive detection of methotrexate based on fluorescence technology and deep learning algorithms.
Analytica chimica acta
Aug 8, 2025
BACKGROUND: Methotrexate (MTX) in the body can result in severe, potentially life-threatening side effects. As a result, it is imperative to establish a dependable, precise, and specific method for detecting MTX. However, conventional sensors often s...
Stability and compatibility of methotrexate and dexamethasone in 0.9% sodium chloride for intrathecal injection.
Pakistan journal of pharmaceutical sciences
Nov 1, 2020
The stability of a mixture of methotrexate and dexamethasone sodium phosphate in 0.9% sodium chloride for intrathecal (IT) injection was assessed. To simulate the clinically used concentrations of the admixtures, 2mL of 0.9% sodium chloride was added...
Mangosteen ethanol extract alleviated the severity of collagen-induced arthritis in rats and produced synergistic effects with methotrexate.
Pharmaceutical biology
Dec 1, 2018
CONTEXT: Garcinia mangostana Linn. (Guttiferae) pericarp is used as a traditional medicine in South Asia to treat inflammatory diseases.
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