AIMC Topic: Mice
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Automatic identification of crossovers in cryo-EM images of murine amyloid protein A fibrils with machine learning.
Journal of microscopy
Dec 29, 2019
Detecting crossovers in cryo-electron microscopy images of protein fibrils is an important step towards determining the morphological composition of a sample. Currently, the crossover locations are picked by hand, which introduces errors and is a tim...
Machine Learning-Based Classification of the Health State of Mice Colon in Cancer Study from Confocal Laser Endomicroscopy.
Scientific reports
Dec 27, 2019
In this article, we address the problem of the classification of the health state of the colon's wall of mice, possibly injured by cancer with machine learning approaches. This problem is essential for translational research on cancer and is a priori...
A novel machine learning based approach for iPS progenitor cell identification.
PLoS computational biology
Dec 26, 2019
Identification of induced pluripotent stem (iPS) progenitor cells, the iPS forming cells in early stage of reprogramming, could provide valuable information for studying the origin and underlying mechanism of iPS cells. However, it is very difficult ...
Mitochondria Segmentation From EM Images via Hierarchical Structured Contextual Forest.
IEEE journal of biomedical and health informatics
Dec 23, 2019
Delineation of mitochondria from electron microscopy (EM) images is crucial to investigate its morphology and distribution, which are directly linked to neural dysfunction. However, it is a challenging task due to the varied appearances, sizes and sh...
Visual Servoed Robotic Mouse Oocyte Rotation.
IEEE transactions on bio-medical engineering
Dec 23, 2019
UNLABELLED: Both injection and biopsy of a mammalian cell require positioning and orientation of a biological cell in a three-dimensional space under a microscope. Manual cell manipulation and orientation is the most commonly used method that is base...
Bio-transformation of green tea infusion with tannase and its improvement on adipocyte metabolism.
Enzyme and microbial technology
Dec 23, 2019
Catechins in green tea possess various health benefits. Enzymatic treatment improves physiological activities by inducing bioconversion of catechins. Here, we investigated the effect of green tea infusion (GT) after tannase treatment, which transform...
Super-Soft and Super-Elastic DNA Robot with Magnetically Driven Navigational Locomotion for Cell Delivery in Confined Space.
Angewandte Chemie (International ed. in English)
Dec 23, 2019
Soft organisms such as earthworms can access confined, narrow spaces, inspiring scientists to fabricate soft robots for in vivo manipulation of cells or tissues and minimally invasive surgery. We report a super-soft and super-elastic magnetic DNA hyd...
Efficient identification of novel anti-glioma lead compounds by machine learning models.
European journal of medicinal chemistry
Dec 19, 2019
Glioblastoma multiforme (GBM) is the most devastating and widespread primary central nervous system tumor. Pharmacological treatment of this malignance is limited by the selective permeability of the blood-brain barrier (BBB) and relies on a single d...
A novel Cerenkov luminescence tomography approach using multilayer fully connected neural network.
Physics in medicine and biology
Dec 19, 2019
Cerenkov luminescence tomography (CLT) has been proved as an effective tool for various biomedical applications. Because of the severe scattering of Cerenkov luminescence, the performance of CLT remains unsatisfied. This paper proposed a novel CLT re...
Epigallocatechin gallate has antibacterial and antibiofilm activity in methicillin resistant and susceptible of different lineages in non-cytotoxic concentrations.
Natural product research
Dec 9, 2019
is an opportunistic agent that can cause a variety of infections, both hospital and community-acquired. Epigallocatechin gallate (EGCG), a flavonoid present in the leaves of , has different biological activities, including antimicrobial potential. H...
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