Interdisciplinary sciences, computational life sciences
Dec 15, 2023
Since the identification of microRNAs (miRNAs), empirical research has demonstrated their crucial involvement in the functioning of organisms. Investigating miRNAs significantly bolsters efforts related to averting, diagnosing, and treating intricate...
False results and time delay are longstanding challenges in biosensing. While classification models and deep learning may provide new opportunities for improving biosensor performance, such as measurement confidence and speed, it remains a challenge ...
SLAS discovery : advancing life sciences R & D
Oct 14, 2023
MicroRNAs (miRNAs) play a crucial role in post-transcriptional gene regulation and have been implicated in various diseases, including cancers and lung disease. In recent years, Graph Neural Networks (GNNs) have emerged as powerful tools for analyzin...
IEEE/ACM transactions on computational biology and bioinformatics
Oct 9, 2023
The circRNAs and miRNAs play an important role in the development of human diseases, and they can be widely used as biomarkers of diseases for disease diagnosis. In particular, circRNAs can act as sponge adsorbers for miRNAs and act together in certa...
In recent years, due to the contribution to elucidating the functional mechanisms of miRNAs and lncRNAs, the research on miRNA-lncRNA interaction prediction has increased exponentially. However, the prediction research is challenging in bioinformatic...
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry
Sep 13, 2023
OBJECTIVES: This study aimed at identifying reliable differentially expressed miRNAs (DEMs) for schizophrenia in blood meta-analyses combined with deep learning methods.
Journal of cancer research and clinical oncology
Sep 7, 2023
PURPOSE: Skin cutaneous melanoma (SKCM) is a highly aggressive melanocytic carcinoma whose high heterogeneity and complex etiology make its prognosis difficult to predict. This study aimed to construct a risk subtype typing model for SKCM.
Journal of biomolecular structure & dynamics
Jul 14, 2023
Marfan syndrome (MFS) is a hereditary disease with high mortality. This study aimed to explore peripheral blood potential markers and underlying mechanisms in MFS via a series bioinformatics and machine learning analysis. First, we downloaded two MFS...
MicroRNAs have a significant role in the emergence of various human disorders. Consequently, it is essential to understand the existing interactions between miRNAs and diseases, as this will help scientists better study and comprehend the diseases' b...
BACKGROUND: The discovery of a saliva-based micro–ribonucleic acid (miRNA) signature for endometriosis in 2022 opened up new perspectives for early and noninvasive diagnosis of the disease. The 109-miRNA saliva signature is the product of miRNA bioma...