Clinica chimica acta; international journal of clinical chemistry
Sep 29, 2025
Psoriasis, a T-helper mediated chronic inflammatory autoimmune skin disease, has significant socioeconomic burden worldwide. Unfortunately, its etiology and underlying pathophysiology remains unclear. Although several biologics have substantially imp...
Journal of molecular neuroscience : MN
Aug 27, 2025
Low-grade gliomas (LGGs) represent a complex and aggressive category of brain tumors. Despite recent advancements in molecular subtyping and characterization, the necessity to identify additional molecular subtypes and biomarkers remains. To delineat...
BACKGROUND: Renal cell carcinoma (RCC) is a prevalent malignancy with highly variable outcomes. MicroRNA-15a (miR-15a) has emerged as a promising prognostic biomarker in RCC, linked to angiogenesis, apoptosis, and proliferation. Radiogenomics integra...
Retinopathy of prematurity (ROP) develops in some premature infants and may be characterized by permanent severe retinal damage necessitating early detection and prompt treatment. The purpose of this study was to investigate whether specific miRNAs i...
Prostate cancer (PCa) diagnosis remains challenging due to overlapping clinical features with benign prostatic hyperplasia (BPH) and limitations of existing diagnostic tools like PSA tests, which yield high false-positive rates. This study investigat...
The co-occurrence of osteoporosis (OP) and type 1 diabetes mellitus (T1DM) represents a clinically significant comorbidity pattern, characterized by skeletal fragility and insulin deficiency. While epidemiological links exist, their shared molecular ...
BACKGROUND: Abnormal hedgehog (Hh) signaling is linked to preeclampsia (PE). This study aimed to identify Hh-related diagnostic biomarkers for PE and assess the role of immune infiltration.
Pancreatic cancer (PC) is a highly aggressive malignancy in humans, where early diagnosis significantly improves patient outcomes. However, effective methods for accurate and early detection remain limited. In this multiethnic study involving human s...
The integration of heterogeneous multi-omics datasets at a systems level remains a central challenge for developing analytical and computational models in precision cancer diagnostics. This paper introduces Multi-Omics Graph Kolmogorov-Arnold Network...
Oral cancer is among the top malignancies and the leading cause of death worldwide. Poor outcomes are attributed to local recurrence and distant metastasis of disease. There is an urgent need to identify the potential biomarkers that may help in prog...
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