AIMC Topic: Microscopy

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Evaluation of Scopio Labs X100 Full Field PBS: The first high-resolution full field viewing of peripheral blood specimens combined with artificial intelligence-based morphological analysis.

International journal of laboratory hematology
BACKGROUND: Current digital cell imaging systems perform peripheral blood smear (PBS) analysis in limited regions of the PBS and require the support of manual microscopy without achieving full digital microscopy. We report a multicenter study that va...

Deep-learning on-chip light-sheet microscopy enabling video-rate volumetric imaging of dynamic biological specimens.

Lab on a chip
Volumetric imaging of dynamic signals in a large, moving, and light-scattering specimen is extremely challenging, owing to the requirement on high spatiotemporal resolution and difficulty in obtaining high-contrast signals. Here we report that throug...

Quantitative particle agglutination assay for point-of-care testing using mobile holographic imaging and deep learning.

Lab on a chip
Particle agglutination assays are widely adopted immunological tests that are based on antigen-antibody interactions. Antibody-coated microscopic particles are mixed with a test sample that potentially contains the target antigen, as a result of whic...

Misic, a general deep learning-based method for the high-throughput cell segmentation of complex bacterial communities.

eLife
Studies of bacterial communities, biofilms and microbiomes, are multiplying due to their impact on health and ecology. Live imaging of microbial communities requires new tools for the robust identification of bacterial cells in dense and often inter-...

Skin cancer classification via convolutional neural networks: systematic review of studies involving human experts.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Multiple studies have compared the performance of artificial intelligence (AI)-based models for automated skin cancer classification to human experts, thus setting the cornerstone for a successful translation of AI-based tools into clinic...

Mobile microscopy and telemedicine platform assisted by deep learning for the quantification of Trichuris trichiura infection.

PLoS neglected tropical diseases
Soil-transmitted helminths (STH) are the most prevalent pathogens among the group of neglected tropical diseases (NTDs). The Kato-Katz technique is the diagnosis method recommended by the World Health Organization (WHO) although it often presents a d...

Helminth egg analysis platform (HEAP): An opened platform for microscopic helminth egg identification and quantification based on the integration of deep learning architectures.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi
BACKGROUND: Millions of people throughout the world suffer from parasite infections. Traditionally, technicians use manual eye inspection of microscopic specimens to perform a parasite examination. However, manual operations have limitations that hin...

Automated detection of superficial fungal infections from microscopic images through a regional convolutional neural network.

PloS one
Direct microscopic examination with potassium hydroxide is generally used as a screening method for diagnosing superficial fungal infections. Although this type of examination is faster than other diagnostic methods, it can still be time-consuming to...

Robust deep learning optical autofocus system applied to automated multiwell plate single molecule localization microscopy.

Journal of microscopy
We presenta robust, long-range optical autofocus system for microscopy utilizing machine learning. This can be useful for experiments with long image data acquisition times that may be impacted by defocusing resulting from drift of components, for ex...

Vesseg: An Open-Source Tool for Deep Learning-Based Atherosclerotic Plaque Quantification in Histopathology Images-Brief Report.

Arteriosclerosis, thrombosis, and vascular biology
Objective: Manual plaque segmentation in microscopy images is a time-consuming process in atherosclerosis research and potentially subject to unacceptable user-to-user variability and observer bias. We address this by releasing Vesseg a tool that inc...