OBJECTIVES/HYPOTHESIS: Machine learning (ML) is a type of artificial intelligence wherein a computer learns patterns and associations between variables to correctly predict outcomes. The objectives of this study were to 1) use a ML platform to identi...
Laboratory investigation; a journal of technical methods and pathology
Jun 14, 2019
Microvascularity is highly correlated with the grading and subtyping of gliomas, making this one of its most important histological features. Accurate quantitative analysis of microvessels is helpful for the development of a targeted therapy for anti...
IEEE/ACM transactions on computational biology and bioinformatics
May 2, 2019
While coronary microvascular dysfunction (CMD) is a major cause of ischemia, it is very challenging to diagnose due to lack of CMD-specific screening measures. CMD has been identified as one of the five priority areas of investigation in a 2014 Natio...
IEEE transactions on bio-medical engineering
Mar 9, 2018
UNLABELLED: Vascular ageing is known to be accompanied by arterial stiffening and vascular endothelial dysfunction, and represents an independent factor contributing to the development of cardiovascular disease. The microvascular pulse is affected by...
BACKGROUND: Pathological angiogenesis has been identified in many malignancies as a potential prognostic factor and target for therapy. In most cases, angiogenic analysis is based on the measurement of microvessel density (MVD) detected by immunostai...
Whole-slide imaging of histologic sections captures tissue microenvironments and cytologic details in expansive high-resolution images. These images can be mined to extract quantitative features that describe tissues, yielding measurements for hundre...
RATIONALE AND OBJECTIVES: This study aims to develop and validate a deep learning radiomics signature (DLRS) that integrates radiomics and deep learning features for the non-invasive prediction of microvascular invasion (MVI) in patients with colon c...
Journal of cellular and molecular medicine
Aug 1, 2025
Liver resection remains the mainstay curative treatment for hepatocellular carcinoma (HCC); however, the recurrence rate is reported to exceed 70% within 5 years after surgery. Microvascular invasion (MVI) has attracted great research interest in the...
IEEE transactions on bio-medical engineering
Jun 1, 2025
Microvascular invasion (MVI) of hepatocellular carcinoma (HCC) is a crucial histopathologic prognostic factor associated with cancer recurrence after liver transplantation or hepatectomy. Recently, clinicoradiologic characteristics are combined with ...
To address inter-frame motion artifacts in ultrasound quantitative high-definition microvasculature imaging (qHDMI), we introduced a novel deep learning-based motion correction technique. This approach enables the derivation of more accurate quantita...
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