PURPOSE: To investigate whether corneal changes observed via in vivo confocal microscopy (IVCM) in patients with aniridia-related keratopathy (ARK) reflect clinical severity.
OBJECTIVES: To develop and validate a machine learning model for precise risk stratification of postpancreaticoduodenectomy haemorrhage (PPH), enabling early identification of high-risk patients to guide clinical intervention.
BACKGROUND: Patients with cancer and cancer survivors often experience multiple chronic health conditions, which can impact symptom burden and treatment outcomes. Despite the high prevalence of multimorbidity, research on cancer prognosis has predomi...
BACKGROUND: Wearable devices are increasingly used for monitoring health and detecting digital biomarkers related to chronic diseases such as metabolic syndrome (MetS). Although circadian rhythm disturbances are known to contribute to MetS, few studi...
BACKGROUND: Syndrome differentiation in traditional Chinese medicine (TCM) is an ancient principle that guides disease diagnosis and treatment. Among these, the cold and hot syndromes play a crucial role in identifying the nature of the disease and g...
BACKGROUND AND OBJECTIVE: Degenerative cerebellar ataxia, a group of progressive neurodegenerative disorders, is characterised by cerebellar atrophy and impaired motor learning. Using CerebNet, a deep learning algorithm for cerebellar segmentation, t...
BACKGROUND: Sepsis-associated delirium (SAD) occurs due to disruptions in neurotransmission linked to inflammatory responses from infections. It poses significant challenges in clinical management and is associated with poor outcomes. Survivors often...
Immunotherapy has become a cornerstone in the treatment of advanced gastric cancer (GC). However, identifying reliable predictive biomarkers remains a considerable challenge. This study demonstrates the potential of integrating multimodal baseline da...
Clinica chimica acta; international journal of clinical chemistry
Jul 15, 2025
OBJECTIVE: Immunoglobulin D (IgD) myeloma is a rare subtype of multiple myeloma (MM), comprising approximately 1 %-2 % of all MM cases. Owing to the diminished levels of IgD in serum, IgD MM manifests as subtle M protein spikes in routine serum elect...
We aimed to explore the metabolic dysregulations and diagnostic biomarkers for post-traumatic deep venous thrombosis (pt-DVT) in hypertensive (HPT) patients after fracture. An untargeted ultraperformance liquid chromatography-mass spectrometry-based ...
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