AIMC Topic: Middle Aged

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Predicting SARS-CoV-2-specific CD4 and CD8 T-cell responses elicited by inactivated vaccines in healthy adults using machine learning models.

Clinical and experimental medicine
The ongoing evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlights the importance of monitoring immune responses to guide vaccination strategies. Although neutralizing antibodies (NAbs) have garnered increasing ...

Evaluating cell-free DNA integrity index as a non-invasive biomarker for neoadjuvant chemotherapy in colorectal cancer patients.

BMC cancer
BACKGROUND: Neoadjuvant chemotherapy (NAC) is gaining attention as a treatment for advanced colorectal cancer owing to its potential to improve surgical outcomes and prognosis. However, reliable biomarkers to predict the response to NAC are lacking. ...

Deep learning-based allergic rhinitis diagnosis using nasal endoscopy images.

Scientific reports
Allergic rhinitis typically has edematous and pale turbinates or erythematous and inflamed turbinates. While traditional approaches include using skin prick tests (SPT) to determine the presence of AR, It is often not related to actual symptoms, and ...

Fairness of machine learning readmission predictions following open ventral hernia repair.

Surgical endoscopy
INTRODUCTION: Few models have predicted readmission following open ventral hernia repair (VHR), and none have assessed fairness. Fairness evaluation assesses whether predictive performance is similar across demographic groups, ensuring that biases ar...

Multilayer perceptron deep learning radiomics model based on Gd-BOPTA MRI to identify vessels encapsulating tumor clusters in hepatocellular carcinoma: a multi-center study.

Cancer imaging : the official publication of the International Cancer Imaging Society
OBJECTIVES: The purpose of this study is to mainly develop a predictive model based on clinicoradiological and radiomics features from preoperative gadobenate-enhanced (Gd-BOPTA) magnetic resonance imaging (MRI) using multilayer perceptron (MLP) deep...

Gender difference in cross-sectional area and fat infiltration of thigh muscles in the elderly population on MRI: an AI-based analysis.

European radiology experimental
BACKGROUND: Aging alters musculoskeletal structure and function, affecting muscle mass, composition, and strength, increasing the risk of falls and loss of independence in older adults. This study assessed cross-sectional area (CSA) and fat infiltrat...

Machine learning identifies KRT8 dysregulation and endothelial remodeling in Moyamoya disease.

Scientific reports
Moyamoya disease (MMD) is a rare occlusive cerebrovascular disease, and its pathological mechanism remains unclear at present. The abnormal vascular remodeling may be involved in vascular endothelial cells. In this study, RNA seq was performed on the...

Deep learning-based video analysis for automatically detecting penetration and aspiration in videofluoroscopic swallowing study.

Scientific reports
The videofluoroscopic swallowing study (VFSS) is the gold standard for diagnosing dysphagia, but its interpretation is time-consuming and requires expertise. This study developed a deep learning model for automatically detecting penetration and aspir...

Cost-effectiveness analysis of robotic exoskeleton versus conventional physiotherapy for stroke rehabilitation in Singapore from a health system perspective.

BMJ open
OBJECTIVES: This study conducted a comprehensive probabilistic cost-effectiveness analysis comparing robotic exoskeleton therapy to conventional physiotherapy for stroke rehabilitation in Singapore, focusing on three patient groups categorised by the...