AIMC Topic: Mitochondria
Clear Filters Showing 81 to 90 of 110 articles
Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning.
Biochimica et biophysica acta
Nov 13, 2014
Understanding the processes of mitochondrial dynamics (fission, fusion, biogenesis, and mitophagy) has been hampered by the lack of automated, deterministic methods to measure mitochondrial morphology from microscopic images. A method to quantify mit...
Cell Survival
Membrane Potential, Mitochondrial
Artificial Intelligence
Oxidants
Phenotype
Sodium-Potassium-Exchanging ATPase
Mitochondria
Animals
tert-Butylhydroperoxide
Stress, Physiological
Imaging, Three-Dimensional
Cell Membrane
Carbonyl Cyanide m-Chlorophenyl Hydrazone
Mice
Electron Transport
Cell Respiration
Cell Line
Protein submitochondrial localization from integrated sequence representation and SVM-based backward feature extraction.
Molecular bioSystems
Oct 21, 2014
Mitochondrion, a tiny energy factory, plays an important role in various biological processes of most eukaryotic cells. Mitochondrial defection is associated with a series of human diseases. Knowledge of the submitochondrial locations of proteins can...
Deep learning-driven automated mitochondrial segmentation for analysis of complex transmission electron microscopy images.
Scientific reports
May 30, 2025
Mitochondria are central to cellular energy production and regulation, with their morphology tightly linked to functional performance. Precise analysis of mitochondrial ultrastructure is crucial for understanding cellular bioenergetics and pathology....
The role of mitochondrial dysfunction in the pathogenesis of atherosclerosis: A new exploration from bioinformatics analysis.
Medicine
May 30, 2025
Atherosclerosis (AS) is a complex cardiovascular disease associated with mitochondrial dysfunction (MD), which contributes to plaque formation and instability. This study explores the relationship and shared risk factors between the pathogenesis of A...
Single-cell mitochondrial morphomics reveals cellular heterogeneity and predicts complex I, III, and ATP synthase Inhibition responses.
Scientific reports
May 14, 2025
Mitochondrial heterogeneity drives diverse cellular responses in neurodegenerative diseases, complicating the evaluation of mitochondrial dysfunction. In this study, we describe a high-throughput imaging and analysis approach to investigate cell-to-c...
CHCHD4 Oxidoreductase Activity: A Comprehensive Analysis of the Molecular, Functional, and Structural Properties of Its Redox-Regulated Substrates.
Molecules (Basel, Switzerland)
May 10, 2025
The human CHCHD4 protein, which is a prototypical family member, carries a coiled-coil-helix-coiled-coil-helix motif that is stabilized by two disulfide bonds. Using its CPC sequence motif, CHCHD4 plays a key role in mitochondrial metabolism, cell su...
Machine Learning Assisted Stroke Prediction in Mechanical Circulatory Support: Predictive Role of Systemic Mitochondrial Dysfunction.
ASAIO journal (American Society for Artificial Internal Organs : 1992)
May 1, 2025
Stroke continues to be a major adverse event in advanced congestive heart failure (CHF) patients after continuous-flow left ventricular assist device (CF-LVAD) implantation. Abnormalities in mitochondrial oxidative phosphorylation (OxPhos) have been ...
Oxidative Phosphorylation Pathway in Ankylosing Spondylitis: Multi-Omics Analysis and Machine Learning.
International journal of rheumatic diseases
May 1, 2025
INTRODUCTION: Ankylosing spondylitis (AS) is a chronic inflammatory disease affecting the axial skeleton, characterized by immune microenvironment dysregulation and elevated cytokines like TNF-α and IL-17. Mitochondrial oxidative phosphorylation (OXP...
Screening of mitochondrial-related biomarkers connected with immune infiltration for acute respiratory distress syndrome through WGCNA and machine learning.
Medicine
Mar 7, 2025
Septic acute respiratory distress syndrome (ARDS) is a complex and noteworthy type, but its molecular mechanism has not been fully elucidated. The aim is to explore specific biomarkers to diagnose sepsis-induced ARDS. Gene expression data of sepsis a...
Predicting depression severity using machine learning models: Insights from mitochondrial peptides and clinical factors.
PloS one
Jan 1, 2025
Depression presents a significant challenge to global mental health, often intertwined with factors including oxidative stress. Although the precise relationship with mitochondrial pathways remains elusive, recent advances in machine learning present...
Stay Ahead of Medical AI
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.
Subscribe NowPopular Topics
- Machine Learning 31032
- Neural Networks, Computer 29717
- Algorithms 26831
- Deep Learning 26345
- Artificial Intelligence 24290
- Robotics 13311
- Image Processing, Computer-Assisted 9521
- Retrospective Studies 9110
- Magnetic Resonance Imaging 6181
- Reproducibility of Results 5592
- Tomography, X-Ray Computed 4770
- Support Vector Machine 4686
- Computational Biology 4236
- Brain 4050
- Computer Simulation 3881
Recent Journals
- Scientific reports 5940
- Sensors (Basel, Switzerland) 4794
- PloS one 4015
- Neural networks : the official journal of the International Neural Network Society 2929
- Computational intelligence and neuroscience 1931
- Computers in biology and medicine 1854
- Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference 1686
- Studies in health technology and informatics 1278
- IEEE journal of biomedical and health informatics 1130
- Journal of chemical information and modeling 998
- Nature communications 943
- Computer methods and programs in biomedicine 883
- Bioinformatics (Oxford, England) 861
- Briefings in bioinformatics 853
- IEEE transactions on neural networks and learning systems 826