Traditional survival predictions for oral squamous cell carcinoma (OSCC) rely on TNM staging, which lacks individualized prognostic value. Clinical factors such as performance status, age, sex, and lifestyle affect outcomes but are underrepresented i...
Precancerous tongue lesion is a prevalent, complex, and highly perilous kind of cancer. The tumour might be in the salivary glands, tonsils, neck, cheek, and mouth. Oral Cancer (OC) is commonly identified in advanced stages due to the limited accurac...
International journal of pharmaceutics
Nov 15, 2025
Oral cancer remains one of the most aggressive malignancies worldwide, with high recurrence and limited treatment outcomes due to late diagnosis and ineffective targeting of tumor microenvironments. Stem cell-based hydrogel therapies have emerged as ...
OBJECTIVES: To evaluate the diagnostic potential of surface texture features extracted from clinical images in objectively differentiating benign from malignant oral lesions, and to validate classification performance of a Support Vector Machine (SVM...
This study explores the association of lipid metabolism disruption and Oral Squamous Cell Carcinoma (OSCC). We aim to identify specific lipid biomarkers and therapeutic targets for OSCC. We included 78 OSCC patients and 80 healthy controls, and appli...
Computer vision adjunctive technology for oral lesion diagnoses has been developed to detect and identify Oral Potentially Malignant Disorders (OPMDs) and non-OPMDs. The early detection of OPMDs can reduce the risk of oral cancer development, improvi...
In this study, we propose a new method for oral cancer detection using a modified Vanilla Convolutional Neural Network (CNN) architecture with incorporated batch normalization, dropout regularization, and a customized design structure for the convolu...
Oral cancer is among the top malignancies and the leading cause of death worldwide. Poor outcomes are attributed to local recurrence and distant metastasis of disease. There is an urgent need to identify the potential biomarkers that may help in prog...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
Jul 14, 2025
Over recent years, surface-enhanced Raman spectroscopy (SERS) has shown its unparalleled sensitivity and molecular specificity in biomedical applications. However, noninvasive and sensitive detection of biomarkers with conventional SERS for oral canc...
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