AIMC Topic: Myocytes, Cardiac
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AI-guided laser purification of human iPSC-derived cardiomyocytes for next-generation cardiac cell manufacturing.
Communications biology
May 13, 2025
Current methods for producing cardiomyocytes from human induced pluripotent stem cells (hiPSCs) using 2D monolayer differentiation are often hampered by batch-to-batch variability and inefficient purification processes. Here, we introduce CM-AI, a no...
Identification of key genes and immune infiltration mechanisms in limb ischemia-reperfusion injury: a bioinformatics and experimental study.
Frontiers in immunology
Jan 1, 2025
AIM OF THE STUDY: To establish a cross-tissue bioinformatics model for identifying conserved key genes and immune infiltration mechanisms in ischemia-reperfusion injury (IRI) with experimental validation in limb IRI, including pharmacological targeti...
Classifying Microscopic Acute and Old Myocardial Infarction Using Convolutional Neural Networks.
The American journal of forensic medicine and pathology
Sep 1, 2021
Convolutional neural network (CNN) has advanced in recent years and translated from research into medical practice, most notably in clinical radiology and histopathology. Research on CNNs in forensic/postmortem pathology is almost exclusive to postmo...
aqueous extract attenuates isoproterenol-induced cardiac hypertrophy through the ERK signalling pathway.
Pharmaceutical biology
Dec 1, 2020
CONTEXT: The pharmacological functions of Wall. ex Lindl. (Orchidaceae) in cardiac hypertrophy remains unclear.
Inverse mechano-electrical reconstruction of cardiac excitation wave patterns from mechanical deformation using deep learning.
Chaos (Woodbury, N.Y.)
Dec 1, 2020
The inverse mechano-electrical problem in cardiac electrophysiology is the attempt to reconstruct electrical excitation or action potential wave patterns from the heart's mechanical deformation that occurs in response to electrical excitation. Becaus...
Biohybrid robotics with living cell actuation.
Chemical Society reviews
Jun 22, 2020
As simulators of organisms in Nature, soft robots have been developed over the past few decades. In particular, biohybrid robots constructed by integrating living cells with soft materials demonstrate the unique advantage of simulating the constructi...
[Y-27632 protects H9c2 cardiomyocytes against hypoxia/reoxygenation injury by inhibiting autophagy pathway].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
Nov 1, 2017
Objective To investigate the protective effect of preconditioning with Rho-kinase inhibitor Y-27632 on H9c2 cardiomyocytes against hypoxia/reoxygenation (H/R) injury, and explore its underlying mechanism. Methods H9c2 cardiomyocytes were divided into...
[The research on protective effect of penehyclidine hydrochloride in rats with myocardial ischemia/reperfusion injury].
Zhonghua wei zhong bing ji jiu yi xue
Dec 1, 2015
OBJECTIVE: To compare the protective effect of different dose of penehyclidine hydrochloride (PHC) in rats with myocardial ischemia/reperfusion (I/R) injury.
[Effects of Exogenous Nerve Growth Factor on Late Reperfusion after Myocardial Infarction].
Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi
Dec 1, 2015
This study demonstrates that nerve growth factor (NGF) plays a protective role in myocardial infarction and early reperfusion by reducing the myocardial cell apoptosis and by improving ventricular remodeling and seeks to assess the effects and mechan...
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