Biological skins integrate optical and electrical signaling for dynamic environmental interactions, inspiring the development of artificial photonic ionic skins. However, existing synthetic systems often lack mechanical robustness, fast response, and...
International journal of pharmaceutics
Nov 9, 2025
PURPOSE: Gastric adenocarcinoma is a highly aggressive malignancy characterized by a complex tumor microenvironment. Nano-curcumin liposomes hold great potential in inhibiting tumor growth and survival, as well as inducing cuproptosis and oxidative s...
Allergic skin disease conditions represent a significant global health challenge, with conventional therapies frequently associated with local dermal irritation and systemic adverse effects. Nanotechnology-enabled transdermal drug delivery platforms ...
Cytotoxic T cells (CD8) play a pivotal role in immunosurveillance by identifying and eliminating tumor cells. However, the onset of CD8 T cell exhaustion, characterized by overexpression of immune checkpoint receptors, impairs their function, allowin...
Proceedings of the National Academy of Sciences of the United States of America
Nov 3, 2025
Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generation vaccines due to their ability to induce antibody responses of superior magnitude, breadth, and durability. Computational protein design offers a ro...
Journal of controlled release : official journal of the Controlled Release Society
Nov 1, 2025
Lipid nanoparticles have emerged as valuable gene delivery systems paving the way for next-generation vaccine and cancer therapeutics. Inevitably, this evolution is carried by dissecting and rationalizing the vehicles' complex formulation process. Gi...
Integrating machine learning (ML) into nanotechnology represents a promising strategy for rational design and accelerated development of drug delivery systems. However, studies in this field are scarce and face methodological and interpretative probl...
Developing poly(lactic-co-glycolic) acid (PLGA) nanoparticles with optimized drug encapsulation and loading is crucial for effective drug delivery. However, controlling the physicochemical properties of these nanoparticles remains challenging. In thi...
Wearable acoustic sensors offer a promising solution for effective communication for individuals with speech impairments by calibrating throat vibrations and converting them to synthesized speech. We developed a new type of piezoresistive acoustic se...
Nanoparticle-based therapies have gained attention in recent years as promising treatments for rheumatoid arthritis (RA), due to the potential offered for targeted delivery, controlled drug release, and improved biocompatibility. A deep understanding...
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