AIMC Topic: Nanoparticles
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Cell Response to Nanoplastics and Their Carrier Effects Tracked Real-Timely with Machine Learning-Driven Smart Surface-Enhanced Raman Spectroscopy Slides.
Analytical chemistry
Apr 4, 2025
Research on nanoplastic (NP) toxicity and their "carrier effects" on human health remains nascent, especially for real-time, in situ monitoring of metabolic reactions in live cells. Herein, we developed smart surface-enhanced Raman spectroscopy (SERS...
Biofilm-mediated infections; novel therapeutic approaches and harnessing artificial intelligence for early detection and treatment of biofilm-associated infections.
Microbial pathogenesis
Mar 19, 2025
A biofilm is a group of bacteria that have self-produced a matrix and are grouped together in a dense population. By resisting the host's immune system's phagocytosis process and attacking with anti-microbial chemicals such as reactive oxygen and nit...
Utilization of machine learning approach for production of optimized PLGA nanoparticles for drug delivery applications.
Scientific reports
Mar 14, 2025
This study investigates utilization of machine learning for the regression task of predicting the size of PLGA (Poly lactic-co-glycolic acid) nanoparticles. Various inputs including category and numeric were considered for building the model to predi...
AI-driven innovations in smart multifunctional nanocarriers for drug and gene delivery: A mini-review.
Critical reviews in oncology/hematology
Mar 13, 2025
The convergence of artificial intelligence (AI) and nanomedicine has revolutionized the design of smart multifunctional nanocarriers (SMNs) for drug and gene delivery, offering unprecedented precision, efficiency, and personalization in therapeutic a...
Deep Learning Enhanced Near Infrared-II Imaging and Image-Guided Small Interfering Ribonucleic Acid Therapy of Ischemic Stroke.
ACS nano
Mar 5, 2025
Small interfering RNA (siRNA) targeting the NOD-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome has emerged as a promising therapeutic strategy to mitigate infarct volume and brain injury following ischemic stroke. However, the cl...
Machine learning-assisted design of immunomodulatory lipid nanoparticles for delivery of mRNA to repolarize hyperactivated microglia.
Drug delivery
Mar 3, 2025
Regulating inflammatory microglia presents a promising strategy for treating neurodegenerative and autoimmune disorders, yet effective therapeutic agents delivery to these cells remains a challenge. This study investigates modified lipid nanoparticle...
Comparative immobilization of 30 PFAS mixtures onto biochar, clay, nanoparticle, and polymer derived engineered adsorbents: Machine learning insights into carbon chain length and removal mechanism.
Journal of hazardous materials
Feb 25, 2025
Per- and polyfluoroalkyl substances (PFAS) are a group of fluorinated chemicals that cause potential risk in PFAS-impacted soil and water. The adsorption efficiency of 30 PFAS mixtures using different adsorbents in environmentally relevant concentrat...
Optimizing thermal dose prediction in nanoparticle-mediated photothermal therapy using a convolutional neural network-based model.
Journal of thermal biology
Feb 22, 2025
Nanoparticle-mediated photothermal therapy (NMPTT) is an up-and-coming targeted cancer treatment. Here, nanoparticles are used to convert near-infrared light into localized heat that can kill tumour cells while sparing surrounding healthy tissue. Nev...
High throughput analysis of rare nanoparticles with deep-enhanced sensitivity via unsupervised denoising.
Nature communications
Feb 20, 2025
The large-scale multiparametric analysis of individual nanoparticles is increasingly vital in the diverse fields of biology, medicine, and materials science. However, the current methods struggle with the tradeoff between measurement scalability and ...
Revolutionizing prostate cancer therapy: Artificial intelligence - Based nanocarriers for precision diagnosis and treatment.
Critical reviews in oncology/hematology
Feb 7, 2025
Prostate cancer is one of the major health challenges in the world and needs novel therapeutic approaches to overcome the limitations of conventional treatment. This review delineates the transformative potential of artificial intelligence (AL) in en...
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