AIMC Topic: Neoplastic Cells, Circulating

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Photoelectrochemical detection of circulating tumor cells based on aptamer conjugated CuO as signal probe.

Biosensors & bioelectronics
In this work, a sensitive and reliable photoelectrochemical (PEC) biosensor was proposed based on hexagonal carbon nitride tubes (HCNT) as photoactive material for detection of circulating tumor cells (CTCs). Magnetic FeO nanospheres (MNs) and CuO na...

Light-driven ultrasensitive self-powered cytosensing of circulating tumor cells via integration of biofuel cells and a photoelectrochemical strategy.

Journal of materials chemistry. B
Herein, a light-driven, membrane-less and mediator-less self-powered cytosensing platform via integration of biofuel cells (BFCs) and a photoelectrochemical strategy was developed for ultrasensitive detection of circulating tumor cells (CTCs). To con...

Multifunctional luminescent immuno-magnetic nanoparticles: toward fast, efficient, cell-friendly capture and recovery of circulating tumor cells.

Journal of materials chemistry. B
Highly efficient isolation and recovery of viable circulating tumor cells (CTCs) from the blood of patients is an important precondition to address the current dilemma of insufficient CTC studies, and can promote the development of individualized ant...

Analogous detection of circulating tumor cells using the AccuCyte -CyteFinder system and ISET system in patients with locally advanced and metastatic prostate cancer.

The Prostate
INTRODUCTION: Circulating tumor cells (CTCs) can provide important information on patient's prognosis and treatment efficacy. Currently, a plethora of methods is available for the detection of these rare cells. We compared the outcomes of two of thos...

Challenges in circulating tumor cell detection by the CellSearch system.

Molecular oncology
Enumeration and characterization of circulating tumor cells (CTC) hold the promise of a real time liquid biopsy. They are however present in a large background of hematopoietic cells making their isolation technically challenging. In 2004, the CellSe...

Automated Classification of Circulating Tumor Cells and the Impact of Interobsever Variability on Classifier Training and Performance.

Journal of immunology research
Application of personalized medicine requires integration of different data to determine each patient's unique clinical constitution. The automated analysis of medical data is a growing field where different machine learning techniques are used to mi...

Emerging biomarkers for pancreatic cancer: from early detection to personalized therapy.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico
Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its poor prognosis and late diagnosis. Biomarkers are essential in enhancing diagnostic accuracy, prognostic assessments, and therapeutic strategies, thereby address...

Metabolic Adaptation Study of Tumor Cells during Lung Cancer Bone Metastasis in Mice Based on Single-Cell Metabolome Analysis.

Journal of the American Society for Mass Spectrometry
Lung cancer metastasis, the leading cause of patient mortality, is driven by circulating tumor cells (CTCs), which act as direct mediators of metastatic spread. To elucidate the metabolic heterogeneity across lung cancer metastatic stages, a panorami...

A cell-interacting and multi-correcting method for automatic circulating tumor cells detection.

Artificial intelligence in medicine
Sensitive detection of circulating tumor cells (CTCs) from peripheral blood can serve as an effective tool in the early diagnosis and prognosis of cancer. Many methods based on modern object detectors were proposed in recent years for automatic abnor...

Cancer in a drop: Advances in liquid biopsy in 2024.

Critical reviews in oncology/hematology
Over the past decade, liquid biopsy (LB) has emerged as a key tool in oncology. Its utility in non-invasive sampling and real-time monitoring has made it a cornerstone in precision medicine. Since 2020, publications on LB in solid tumors have doubled...