AIMC Topic: Predictive Value of Tests

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Machine Learning in Drug Discovery and Development Part 1: A Primer.

CPT: pharmacometrics & systems pharmacology
Artificial intelligence, in particular machine learning (ML), has emerged as a key promising pillar to overcome the high failure rate in drug development. Here, we present a primer on the ML algorithms most commonly used in drug discovery and develop...

Applying deep learning to single-trial EEG data provides evidence for complementary theories on action control.

Communications biology
Efficient action control is indispensable for goal-directed behaviour. Different theories have stressed the importance of either attention or response selection sub-processes for action control. Yet, it is unclear to what extent these processes can b...

Computationally Derived Image Signature of Stromal Morphology Is Prognostic of Prostate Cancer Recurrence Following Prostatectomy in African American Patients.

Clinical cancer research : an official journal of the American Association for Cancer Research
PURPOSE: Between 30%-40% of patients with prostate cancer experience disease recurrence following radical prostatectomy. Existing clinical models for recurrence risk prediction do not account for population-based variation in the tumor phenotype, des...

BrainSpace: a toolbox for the analysis of macroscale gradients in neuroimaging and connectomics datasets.

Communications biology
Understanding how cognitive functions emerge from brain structure depends on quantifying how discrete regions are integrated within the broader cortical landscape. Recent work established that macroscale brain organization and function can be describ...

Improved Accuracy in Optical Diagnosis of Colorectal Polyps Using Convolutional Neural Networks with Visual Explanations.

Gastroenterology
BACKGROUND & AIMS: Narrow-band imaging (NBI) can be used to determine whether colorectal polyps are adenomatous or hyperplastic. We investigated whether an artificial intelligence (AI) system can increase the accuracy of characterizations of polyps b...