AIMC Topic: Prefrontal Cortex

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Hippocampal-prefrontal functional neural networks in a rat model of fragile X syndrome are poorly organized with limited resiliency.

Scientific reports
Fragile X Syndrome (FXS) is a common cause of autism spectrum symptoms. The genetic mutation results in multiple molecular alterations that are hypothesized to negatively impact neural circuit development although the nature of any functional neural ...

Distributed Representations for Cognitive Control in Frontal Medial Cortex.

Journal of cognitive neuroscience
In natural and artificial neural networks, modularity and distributed structure afford complementary but competing benefits. The former allows for hierarchical representations that can flexibly recombine modules to address novel problems, whereas the...

Cortical activation in robot-assisted dynamic and static resistance training combining VR interaction: An fNIRS based pilot study.

NeuroRehabilitation
BACKGROUND: There are few isometric training systems based on upper limb rehabilitation robots. Its efficacy and neural mechanism are not well understood.

Bridging across functional models: The OFC as a value-making neural network.

Behavioral neuroscience
Many functions have been attributed to the orbitofrontal cortex (OFC)-some classical roles, such as signaling the value of action outcomes, being challenged by more recent ones, such as signaling the position of a trial within a task space. In this p...

[Effects of acupuncture on Nod-like receptor protein 3 inflammasome signal pathway in the prefrontal cortex of rat with depression].

Zhen ci yan jiu = Acupuncture research
OBJECTIVE: To observe the influence of acupuncture on the expression of pivotal molecules of Nod-like receptor protein 3(NLRP3) inflammasome signal pathway in the prefrontal cortex of rats with depression, so as to explore the underlying mechanism of...

Changes in Functional Connectivity Predict Outcome of Repetitive Transcranial Magnetic Stimulation Treatment of Major Depressive Disorder.

Cerebral cortex (New York, N.Y. : 1991)
Repetitive transcranial magnetic stimulation (rTMS) treatment of major depressive disorder (MDD) is associated with changes in brain functional connectivity (FC). These changes may be related to the mechanism of action of rTMS and explain the variabi...

Brain stimulation to left prefrontal cortex modulates attentional orienting to gaze cues.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
In social interactions, we rely on non-verbal cues like gaze direction to understand the behaviour of others. How we react to these cues is determined by the degree to which we believe that they originate from an entity with a mind capable of having ...

Predicting Response to Repetitive Transcranial Magnetic Stimulation in Patients With Schizophrenia Using Structural Magnetic Resonance Imaging: A Multisite Machine Learning Analysis.

Schizophrenia bulletin
BACKGROUND: The variability of responses to plasticity-inducing repetitive transcranial magnetic stimulation (rTMS) challenges its successful application in psychiatric care. No objective means currently exists to individually predict the patients' r...

Computing by Robust Transience: How the Fronto-Parietal Network Performs Sequential, Category-Based Decisions.

Neuron
Decision making involves dynamic interplay between internal judgements and external perception, which has been investigated in delayed match-to-category (DMC) experiments. Our analysis of neural recordings shows that, during DMC tasks, LIP and PFC ne...