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Prefrontal Cortex

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Information Content of Prefrontal Cortex Activity Quantifies the Difficulty of Narrated Stories.

Scientific reports
The ability to realize the individuals' impressions during the verbal communication allows social robots to significantly facilitate their social interactions in such areas as child education and elderly care. However, such impressions are highly sub...

The Effects of Population Tuning and Trial-by-Trial Variability on Information Encoding and Behavior.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Identifying the features of population responses that are relevant to the amount of information encoded by neuronal populations is a crucial step toward understanding population coding. Statistical features, such as tuning properties, individual and ...

A neural model of schemas and memory encoding.

Biological cybernetics
The ability to rapidly assimilate new information is essential for survival in a dynamic environment. This requires experiences to be encoded alongside the contextual schemas in which they occur. Tse et al. (Science 316(5821):76-82, 2007) showed that...

Structured sequence processing and combinatorial binding: neurobiologically and computationally informed hypotheses.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences
Understanding how the brain forms representations of structured information distributed in time is a challenging endeavour for the neuroscientific community, requiring computationally and neurobiologically informed approaches. The neural mechanisms f...

Machine learning: assessing neurovascular signals in the prefrontal cortex with non-invasive bimodal electro-optical neuroimaging in opiate addiction.

Scientific reports
Chronic and recurrent opiate use injuries brain tissue and cause serious pathophysiological changes in hemodynamic and subsequent inflammatory responses. Prefrontal cortex (PFC) has been implicated in drug addiction. However, the mechanism underlying...

Neuronal population correlates of target selection and distractor filtering.

NeuroImage
Frontal Eye Field (FEF) neurons discriminate between relevant and irrelevant visual stimuli and their response magnitude predicts conscious perception. How this is reflected in the spatial representation of a visual stimulus at the neuronal populatio...

A neural network for online spike classification that improves decoding accuracy.

Journal of neurophysiology
Separating neural signals from noise can improve brain-computer interface performance and stability. However, most algorithms for separating neural action potentials from noise are not suitable for use in real time and have shown mixed effects on dec...

Unraveling the Mysteries of Motivation.

Trends in cognitive sciences
Motivation plays a central role in human behavior and cognition but is not well captured by widely used artificial intelligence (AI) and computational modeling frameworks. This Opinion article addresses two central questions regarding the nature of m...

Neurotransmitter networks in mouse prefrontal cortex are reconfigured by isoflurane anesthesia.

Journal of neurophysiology
This study quantified eight small-molecule neurotransmitters collected simultaneously from prefrontal cortex of C57BL/6J mice ( = 23) during wakefulness and during isoflurane anesthesia (1.3%). Using isoflurane anesthesia as an independent variable e...

Prefrontal oscillations modulate the propagation of neuronal activity required for working memory.

Neurobiology of learning and memory
Cognition involves using attended information, maintained in working memory (WM), to guide action. During a cognitive task, a correct response requires flexible, selective gating so that only the appropriate information flows from WM to downstream ef...