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Prognosis

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Integrating single-cell sequencing and machine learning to uncover the role of mitophagy in subtyping and prognosis of esophageal cancer.

Apoptosis : an international journal on programmed cell death
Globally, esophageal cancer stands as a prominent contributor to cancer-related fatalities, distinguished by its poor prognosis. Mitophagy has a significant impact on the process of cancer progression. This study investigated the prognostic significa...

Prediction of cognitive conversion within the Alzheimer's disease continuum using deep learning.

Alzheimer's research & therapy
BACKGROUND: Early diagnosis and accurate prognosis of cognitive decline in Alzheimer's disease (AD) is important to timely assignment to optimal treatment modes. We aimed to develop a deep learning model to predict cognitive conversion to guide re-as...

A multicentre implementation trial of an Artificial Intelligence-driven biomarker to inform Shared decisions for androgen deprivation therapy in men undergoing prostate radiotherapy: the ASTuTE protocol.

BMC cancer
BACKGROUND: Androgen deprivation therapy (ADT) improves outcomes in men undergoing definitive radiotherapy for prostate cancer but carries significant toxicities. Clinical parameters alone are insufficient to accurately identify patients who will der...

Machine learning models for prognosis prediction in regenerative endodontic procedures.

BMC oral health
BACKGROUND: This study aimed to establish and validate machine learning (ML) models to predict the prognosis of regenerative endodontic procedures (REPs) clinically, assisting clinicians in decision-making and avoiding treatment failure.

Artificial intelligence in gastrointestinal cancer research: Image learning advances and applications.

Cancer letters
With the rapid advancement of artificial intelligence (AI) technologies, including deep learning, large language models, and neural networks, these methodologies are increasingly being developed and integrated into cancer research. Gastrointestinal t...

Machine learning for the early prediction of long-term cognitive outcome in autoimmune encephalitis.

Journal of psychosomatic research
BACKGROUND AND OBJECTIVE: Autoimmune encephalitis (AE) is an immune-mediated disease. Some patients experience persistent cognitive deficits despite receiving immunotherapy. We aimed to develop a prediction model for long-term cognitive outcomes in p...

Radiomics integration based on intratumoral and peritumoral computed tomography improves the diagnostic efficiency of invasiveness in patients with pure ground-glass nodules: a machine learning, cross-sectional, bicentric study.

Journal of cardiothoracic surgery
BACKGROUND: Radiomics has shown promise in the diagnosis and prognosis of lung cancer. Here, we investigated the performance of computed tomography-based radiomic features, extracted from gross tumor volume (GTV), peritumoral volume (PTV), and GTV + ...

Development of a deep learning system for predicting biochemical recurrence in prostate cancer.

BMC cancer
BACKGROUND: Biochemical recurrence (BCR) occurs in 20%-40% of men with prostate cancer (PCa) who undergo radical prostatectomy. Predicting which patients will experience BCR in advance helps in formulating more targeted prostatectomy procedures. Howe...

Machine learning prediction of breast cancer local recurrence localization, and distant metastasis after local recurrences.

Scientific reports
Local recurrences (LR) can occur within residual breast tissue, chest wall, skin, or newly formed scar tissue. Artificial intelligence (AI) technologies can extract a wide range of tumor features from large datasets helping in oncological decision-ma...

A Deep Reinforcement Learning-Based Feature Selection Method for Invasive Disease Event Prediction Using Imbalanced Follow-Up Data.

IEEE journal of biomedical and health informatics
The machine learning-based model is a promising paradigm for predicting invasive disease events (iDEs) in breast cancer. Feature selection (FS) is an essential preprocessing technique employed to identify the pertinent features for the prediction mod...