AIMC Topic: Proof of Concept Study

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Deep learning-based 3Ddose reconstruction with an electronic portal imaging device for magnetic resonance-linear accelerators: a proof of concept study.

Physics in medicine and biology
To develop a novel deep learning-based 3Ddose reconstruction framework with an electronic portal imaging device (EPID) for magnetic resonance-linear accelerators (MR-LINACs).The proposed method directly back-projected 2D portal dose into 3D patient c...

Deep learning-based classification of kidney transplant pathology: a retrospective, multicentre, proof-of-concept study.

The Lancet. Digital health
BACKGROUND: Histopathological assessment of transplant biopsies is currently the standard method to diagnose allograft rejection and can help guide patient management, but it is one of the most challenging areas of pathology, requiring considerable e...

Automatic Identification of Papillary Projections in Indeterminate Biliary Strictures Using Digital Single-Operator Cholangioscopy.

Clinical and translational gastroenterology
INTRODUCTION: Characterization of biliary strictures is challenging. Papillary projections (PP) are often reported in biliary strictures with high malignancy potential during digital single-operator cholangioscopy. In recent years, the development of...

A multisystem-compatible deep learning-based algorithm for detection and characterization of angiectasias in small-bowel capsule endoscopy. A proof-of-concept study.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND AND AIMS: Current artificial intelligence (AI)-based solutions for capsule endoscopy (CE) interpretation are proprietary. We aimed to evaluate an AI solution trained on a specific CE system (PillcamĀ®, Medtronic) for the detection of angiec...

Learning, visualizing and exploring 16S rRNA structure using an attention-based deep neural network.

PLoS computational biology
Recurrent neural networks with memory and attention mechanisms are widely used in natural language processing because they can capture short and long term sequential information for diverse tasks. We propose an integrated deep learning model for micr...

Deep Learning-Based Automated Thrombolysis in Cerebral Infarction Scoring: A Timely Proof-of-Principle Study.

Stroke
BACKGROUND AND PURPOSE: Mechanical thrombectomy is an established procedure for treatment of acute ischemic stroke. Mechanical thrombectomy success is commonly assessed by the Thrombolysis in Cerebral Infarction (TICI) score, assigned by visual inspe...

Exploring the diagnostic effectiveness for myocardial ischaemia based on CCTA myocardial texture features.

BMC cardiovascular disorders
BACKGROUND: To explore the characteristics of myocardial textures on coronary computed tomography angiography (CCTA) images in patients with coronary atherosclerotic heart disease, a classification model was established, and the diagnostic effectiven...

A proof of concept study for machine learning application to stenosis detection.

Medical & biological engineering & computing
This proof of concept (PoC) assesses the ability of machine learning (ML) classifiers to predict the presence of a stenosis in a three vessel arterial system consisting of the abdominal aorta bifurcating into the two common iliacs. A virtual patient ...

Deep learning in forensic shotgun pattern interpretation - A proof-of-concept study.

Legal medicine (Tokyo, Japan)
Little is known about the potential of artificial intelligence in forensic shotgun pattern interpretation. As shooting distance is among the main factors behind shotgun patterning, this proof-of-concept study aimed to explore the potential of neural ...

Staged reflexive artificial intelligence driven testing algorithms for early diagnosis of pituitary disorders.

Clinical biochemistry
BACKGROUND: Sellar masses (SM) frequently present with insidious hormonal dysfunction. We previously showed that, by utilizing a combined reflex/reflecting approach involving a laboratory clinician (LC) on common endocrine test results requested by n...