AIMC Topic: Propofol

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Improving the anesthetic process by a fuzzy rule based medical decision system.

Artificial intelligence in medicine Jan 5, 2018
OBJECTIVE: The main objective of this research is the design and implementation of a new fuzzy logic tool for automatic drug delivery in patients undergoing general anesthesia. The aim is to adjust the drug dose to the real patient needs using heuris...
Brain Waves Consciousness Monitors Electroencephalography Signal Processing, Computer-Assisted Anesthetics, Intravenous Infusion Pumps Anesthesia, Intravenous Decision Support Systems, Clinical Fuzzy Logic Propofol Predictive Value of Tests Infusions, Intravenous Humans Decision Support Techniques Clinical Decision-Making Middle Aged Time Factors Intraoperative Neurophysiological Monitoring Female Adult Male
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Design and validation of an automated solid phase extraction liquid chromatography coupled mass spectrometry method for the quantification of propofol in plasma.

Journal of pharmaceutical and biomedical analysis Dec 21, 2017
Propofol concentration in human plasma can be quantified by liquid chromatography coupled mass spectrometry. Sample preparation usually requires solid phase extraction to remove matrix components and enrich the analyte. To facilitate user-independent...
Linear Models Calibration Reference Standards Chromatography, Liquid Humans Limit of Detection Automation, Laboratory Workflow Reproducibility of Results Mass Spectrometry Anesthetics, Intravenous Propofol Solid Phase Extraction
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A pilot study of upper airway management using a remote-controlled artificial muscle device during propofol anesthesia.

Journal of clinical anesthesia Feb 9, 2016
STUDY OBJECTIVE: To test the hypothesis that the jaw closure using a pneumatic actuator device affect airway collapsibility and resistance during propofol anesthesia.
Jaw Airway Obstruction Anesthesia, Intravenous Compressed Air Airway Resistance Airway Management Head Movements Male Pilot Projects Propofol Robotics Anesthetics, Intravenous Humans Young Adult Adult
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Preoperative dexmedetomidine attenuates hemodynamic responses to hydrodissection in patients undergoing robotic thyroidectomy.

Journal of anesthesia Sep 28, 2014
PURPOSE: Percutaneous tunneling (hydrodissection) in the neck and anterior chest in patients undergoing robotic thyroidectomy leads to significant hemodynamic responses such as increases in blood pressure and heart rate. We evaluated whether a single...
Double-Blind Method Hemodynamics Dexmedetomidine Humans Perioperative Care Female Thyroidectomy Prospective Studies Adrenergic alpha-2 Receptor Agonists Young Adult Anesthetics, Intravenous Propofol Adult Piperidines Remifentanil Male Anesthesia, Intravenous Robotics Middle Aged
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Prediction of Postinduction Hypotension by Machine Learning.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference Jul 1, 2024
Post-induction hypotension (PIH) occurs shortly after anesthesia induction and is related to several post-operative complications. Medications delivered during induction and maintenance of anesthesia are significantly related to PIH occurrence, which...
Algorithms Female Male Middle Aged Propofol Hypotension Humans Machine Learning
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Process optimisation: spinal versus general anaesthesia for endourological surgery. A randomised, controlled trial and machine-learning approach.

Anaesthesiology intensive therapy Jan 1, 2024
INTRODUCTION: Data concerning anaesthesia for endourology are rare, and options for it are numerous. Thus, identifying the optimal anaesthesia regimen remains challenging. With this study we aimed to provide the means for selecting optimal anaesthesi...
Remifentanil Anesthetics, Local Anesthesia, General Bupivacaine Anesthesia, Spinal Humans Aged Machine Learning Adult Female Male Middle Aged Propofol Hypotension Urologic Surgical Procedures Prilocaine
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The Performance of an Artificial Neural Network Model in Predicting the Early Distribution Kinetics of Propofol in Morbidly Obese and Lean Subjects.

Anesthesia and analgesia Nov 1, 2020
BACKGROUND: Induction of anesthesia is a phase characterized by rapid changes in both drug concentration and drug effect. Conventional mammillary compartmental models are limited in their ability to accurately describe the early drug distribution kin...
Humans Models, Biological Body Weight Anesthetics, Intravenous Obesity, Morbid Nonlinear Dynamics Male Anesthesia, Intravenous Neural Networks, Computer Middle Aged Blood Circulation Propofol Algorithms Predictive Value of Tests Female Body Composition Reproducibility of Results Adult
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γ-Aminobutyric Acid Type A Receptor Potentiation Inhibits Learning in a Computational Network Model.

Anesthesiology Jul 1, 2018
BACKGROUND: Propofol produces memory impairment at concentrations well below those abolishing consciousness. Episodic memory, mediated by the hippocampus, is most sensitive. Two potentially overlapping scenarios may explain how γ-aminobutyric acid re...
Humans Anesthetics, Intravenous Hippocampus Memory Receptors, GABA-A GABA-A Receptor Agonists Neural Networks, Computer Computer Simulation Learning Propofol Neuronal Plasticity
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Prediction of Bispectral Index during Target-controlled Infusion of Propofol and Remifentanil: A Deep Learning Approach.

Anesthesiology Mar 1, 2018
BACKGROUND: The discrepancy between predicted effect-site concentration and measured bispectral index is problematic during intravenous anesthesia with target-controlled infusion of propofol and remifentanil. We hypothesized that bispectral index dur...
Electroencephalography Registries Anesthetics, Intravenous Anesthesia, Intravenous Deep Learning Adolescent Propofol Remifentanil Infusions, Intravenous Humans Female Aged Aged, 80 and over Young Adult Adult Male Middle Aged
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Feasibility of Automated Propofol Sedation for Transcatheter Aortic Valve Implantation: A Pilot Study.

Anesthesia and analgesia Nov 1, 2017
BACKGROUND: Recently, several trials have shown that closed-loop sedation is feasible. No study has used automated sedation in extremely frail patients, such as those scheduled for transcatheter aortic valve implantation (TAVI). We developed and test...
Risk Factors Aged Aged, 80 and over Male Hemodynamics Pilot Projects Monitoring, Intraoperative Decision Support Systems, Clinical Treatment Outcome Propofol Humans Prospective Studies Female Transcatheter Aortic Valve Replacement Anesthetics, Intravenous Hypnotics and Sedatives Automation Consciousness Monitors Robotics Respiration Elective Surgical Procedures Anesthesia, Intravenous Equipment Design Clinical Alarms Feasibility Studies
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