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Prostatic Neoplasms

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Framework for Deep Learning Based Multi-Modality Image Registration of Snapshot and Pathology Images.

IEEE journal of biomedical and health informatics
Multi-modality image registration is an important task in medical imaging because it allows for information from different domains to be correlated. Histopathology plays a crucial role in oncologic surgery as it is the gold standard for investigating...

Minimizing prostate diffusion weighted MRI examination time through deep learning reconstruction.

Clinical imaging
PURPOSE: To study the diagnostic image quality of high b-value diffusion weighted images (DWI) derived from standard and variably reduced datasets reconstructed with a commercially available deep learning reconstruction (DLR) algorithm.

Unmasking Neuroendocrine Prostate Cancer with a Machine Learning-Driven Seven-Gene Stemness Signature That Predicts Progression.

International journal of molecular sciences
Prostate cancer (PCa) poses a significant global health challenge, particularly due to its progression into aggressive forms like neuroendocrine prostate cancer (NEPC). This study developed and validated a stemness-associated gene signature using adv...

Advancing Anticancer Drug Discovery: Leveraging Metabolomics and Machine Learning for Mode of Action Prediction by Pattern Recognition.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
A bottleneck in the development of new anti-cancer drugs is the recognition of their mode of action (MoA). Metabolomics combined with machine learning allowed to predict MoAs of novel anti-proliferative drug candidates, focusing on human prostate can...

OSAIRIS: Lessons Learned From the Hospital-Based Implementation and Evaluation of an Open-Source Deep-Learning Model for Radiotherapy Image Segmentation.

Clinical oncology (Royal College of Radiologists (Great Britain))
Several studies report the benefits and accuracy of using autosegmentation for organ at risk (OAR) outlining in radiotherapy treatment planning. Typically, evaluations focus on accuracy metrics, and other parameters such as perceived utility and safe...

Achieving accurate prostate auto-segmentation on CT in the absence of MR imaging.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
BACKGROUND: Magnetic resonance imaging (MRI) is considered the gold standard for prostate segmentation. Computed tomography (CT)-based segmentation is prone to observer bias, potentially overestimating the prostate volume by ∼ 30 % compared to MRI. H...

Assessment of a fully-automated diagnostic AI software in prostate MRI: Clinical evaluation and histopathological correlation.

European journal of radiology
OBJECTIVE: This study aims to evaluate the diagnostic performance of a commercial, fully-automated, artificial intelligence (AI) driven software tool in identifying and grading prostate lesions in prostate MRI, using histopathological findings as the...

Machine learning and explainable artificial intelligence to predict pathologic stage in men with localized prostate cancer.

The Prostate
BACKGROUND: Though several nomograms exist, machine learning (ML) approaches might improve prediction of pathologic stage in patients with prostate cancer. To develop ML models to predict pathologic stage that outperform existing nomograms that use r...

Evaluation of the accuracy of automated segmentation based on deep learning for prostate cancer patients.

Medical dosimetry : official journal of the American Association of Medical Dosimetrists
PURPOSE: This study evaluated the accuracy of a commercial deep learning (DL)-based algorithm for segmenting the prostate, seminal vesicles (SV), and organs at risk (OAR) in patients with prostate cancer.