AIMC Topic: Psoriasis

Clear Filters Showing 51 to 60 of 63 articles

Characterization of the abnormal lipid profile in Chinese patients with psoriasis.

International journal of clinical and experimental pathology
Psoriasis is a chronic inflammatory skin disease that has been associated with abnormal lipid metabolism. To characterize the lipid profile in Chinese, 86 patients with psoriasis and 84 healthy control subjects were assessed. Compared with healthy co...

Big data-driven target identification by machine learning: DRD2 as a therapeutic target for psoriasis.

Journal of dermatological science
BACKGROUND: The development of medical treatments has traditionally relied on researchers leveraging scientific knowledge to hypothesize disease mechanisms and identify therapeutic agents. However, the depletion of novel therapeutic targets has becom...

Exploring the toxicological impact of bisphenol a exposure on psoriasis through network toxicology, machine learning, and multi-dimensional bioinformatics analysis.

Journal of environmental management
Psoriasis is a common immune - mediated skin disease, the pathogenesis of which is not completely elucidated. Environmental factors are key to its onset and progression. Bisphenol A (BPA) is a ubiquitous environmental pollutant that endangers human h...

Predicting psoriasis severity using machine learning: a systematic review.

Clinical and experimental dermatology
BACKGROUND: In dermatology, the applications of machine learning (ML), an artificial intelligence (AI) subset that enables machines to learn from experience, have progressed past the diagnosis and classification of skin lesions. A lack of systematic ...

Identification and validation of shared biomarkers and drug repurposing in psoriasis and Crohn's disease: integrating bioinformatics, machine learning, and experimental approaches.

Frontiers in immunology
BACKGROUND: Psoriasis and Crohn's disease (CD) are chronic inflammatory diseases that involve complex immune-mediated mechanisms. Despite clinical overlap and shared genetic predispositions, the molecular pathways connecting these diseases remain inc...

Artificial intelligence in psychodermatology: A brief report of applications and impact in clinical practice.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
BACKGROUND: This report evaluates the potential of artificial intelligence (AI) in psychodermatology, emphasizing its ability to enhance diagnostic accuracy, treatment efficacy, and personalized care. Psychodermatology, which explores the connection ...

Machine learning model quantifies mast cells in biopsies of psoriatic lesions imaged with confocal microscopy.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)

Image-based remote evaluation of PASI scores with psoriasis by the YOLO-v4 algorithm.

Experimental dermatology
As a chronic relapsing disease, psoriasis is characterized by widespread skin lesions. The Psoriasis Area and Severity Index (PASI) is the most frequently utilized tool for evaluating the severity of psoriasis in clinical practice. Nevertheless, long...

[Screening for Characteristic Genes of Different Traditional Chinese Medicine Syndromes of Psoriasis Vulgaris: A Study Based on Bioinformatics and Machine Learning].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition
OBJECTIVE: To screen for the key characteristic genes of the psoriasis vulgaris (PV) patients with different Traditional Chinese Medicine (TCM) syndromes, including blood-heat syndrome (BHS), blood stasis syndrome (BSS), and blood-dryness syndrome (B...

Real-World Screening Data for Liver Fibrosis in Psoriasis Patients Treated with Biologics.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is positively associated with the prevalence and severity of psoriasis. The fibrosis-4 (FIB-4) index was developed to predict significant liver fibrosis. Using the FIB-4 ind...