AIMC Topic: Psychotic Disorders

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Towards Precision Medicine in Psychosis: Benefits and Challenges of Multimodal Multicenter Studies-PSYSCAN: Translating Neuroimaging Findings From Research into Clinical Practice.

Schizophrenia bulletin
In the last 2 decades, several neuroimaging studies investigated brain abnormalities associated with the early stages of psychosis in the hope that these could aid the prediction of onset and clinical outcome. Despite advancements in the field, neuro...

Using Machine Learning and Structural Neuroimaging to Detect First Episode Psychosis: Reconsidering the Evidence.

Schizophrenia bulletin
Despite the high level of interest in the use of machine learning (ML) and neuroimaging to detect psychosis at the individual level, the reliability of the findings is unclear due to potential methodological issues that may have inflated the existing...

Systematic Review of Digital Phenotyping and Machine Learning in Psychosis Spectrum Illnesses.

Harvard review of psychiatry
BACKGROUND: Digital phenotyping is the use of data from smartphones and wearables collected in situ for capturing a digital expression of human behaviors. Digital phenotyping techniques can be used to analyze both passively (e.g., sensor) and activel...

Annotating Temporal Relations to Determine the Onset of Psychosis Symptoms.

Studies in health technology and informatics
For patients with a diagnosis of schizophrenia, determining symptom onset is crucial for timely and successful intervention. In mental health records, information about early symptoms is often documented only in free text, and thus needs to be extrac...

Recurrent Neural Networks in Mobile Sampling and Intervention.

Schizophrenia bulletin
The rapid rise and now widespread distribution of handheld and wearable devices, such as smartphones, fitness trackers, or smartwatches, has opened a new universe of possibilities for monitoring emotion and cognition in everyday-life context, and for...

Brain Age in Early Stages of Bipolar Disorders or Schizophrenia.

Schizophrenia bulletin
BACKGROUND: The greater presence of neurodevelopmental antecedants may differentiate schizophrenia from bipolar disorders (BD). Machine learning/pattern recognition allows us to estimate the biological age of the brain from structural magnetic resona...

Use of Machine Learning to Determine Deviance in Neuroanatomical Maturity Associated With Future Psychosis in Youths at Clinically High Risk.

JAMA psychiatry
IMPORTANCE: Altered neurodevelopmental trajectories are thought to reflect heterogeneity in the pathophysiologic characteristics of schizophrenia, but whether neural indicators of these trajectories are associated with future psychosis is unclear.

A New Machine Learning Framework for Understanding the Link Between Cannabis Use and First-Episode Psychosis.

Studies in health technology and informatics
Lately, several studies started to investigate the existence of links between cannabis use and psychotic disorders. This work proposes a refined Machine Learning framework for understanding the links between cannabis use and 1st episode psychosis. Th...

A clinical perspective on the relevance of research domain criteria in electronic health records.

The American journal of psychiatry
OBJECTIVE: The limitations of the DSM nosology for capturing dimensionality and overlap in psychiatric syndromes, and its poor correspondence to underlying neurobiology, have been well established. The Research Domain Criteria (RDoC), a proposed dime...