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Radiosurgery

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Computational Modeling and AI in Radiation Neuro-Oncology and Radiosurgery.

Advances in experimental medicine and biology
The chapter explores the extensive integration of artificial intelligence (AI) in healthcare systems, with a specific focus on its application in stereotactic radiosurgery. The rapid evolution of AI technology has led to promising developments in thi...

Prediction of treatment response after stereotactic radiosurgery of brain metastasis using deep learning and radiomics on longitudinal MRI data.

Scientific reports
We developed artificial intelligence models to predict the brain metastasis (BM) treatment response after stereotactic radiosurgery (SRS) using longitudinal magnetic resonance imaging (MRI) data and evaluated prediction accuracy changes according to ...

Unlocking the adaptive advantage: correlation and machine learning classification to identify optimal online adaptive stereotactic partial breast candidates.

Physics in medicine and biology
Online adaptive radiotherapy (OART) is a promising technique for delivering stereotactic accelerated partial breast irradiation (APBI), as lumpectomy cavities vary in location and size between simulation and treatment. However, OART is resource-inten...

Artificial intelligence-assisted quantitative CT analysis of airway changes following SABR for central lung tumors.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
INTRODUCTION: Use of stereotactic ablative radiotherapy (SABR) for central lung tumors can result in up to a 35% incidence of late pulmonary toxicity. We evaluated an automated scoring method to quantify post-SABR bronchial changes by using artificia...

Combining Metabolomics and Machine Learning to Identify Diagnostic and Prognostic Biomarkers in Patients with Non-Small Cell Lung Cancer Pre- and Post-Radiation Therapy.

Biomolecules
Lung cancer is the leading cause of cancer-related deaths globally, with non-small cell lung cancer (NSCLC) accounting for over 85% of cases and poor prognosis in advanced stages. This study explored shifts in circulating metabolite levels in NSCLC p...

Machine learning predicts conventional imaging metastasis-free survival (MFS) for oligometastatic castration-sensitive prostate cancer (omCSPC) using prostate-specific membrane antigen (PSMA) PET radiomics.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: This study investigated imaging biomarkers derived from PSMA-PET acquired pre- and post-metastasis-directed therapy (MDT) to predict 2-year metastasis-free survival (MFS), which provides valuable early response assessment to improve patient ...

Enhanced 3D dose prediction for hypofractionated SRS (gamma knife radiosurgery) in brain tumor using cascaded-deep-supervised convolutional neural network.

Physical and engineering sciences in medicine
Gamma Knife radiosurgery (GKRS) is a well-established technique in radiation therapy (RT) for treating small-size brain tumors. It administers highly concentrated doses during each treatment fraction, with even minor dose errors posing a significant ...

AutoCorNN: An Unsupervised Physics-Aware Deep Learning Model for Geometric Distortion Correction of Brain MRI Images Towards MR-Only Stereotactic Radiosurgery.

Journal of imaging informatics in medicine
Geometric distortions in brain MRI images arising from susceptibility artifacts at air-tissue interfaces pose a significant challenge for high-precision radiation therapy modalities like stereotactic radiosurgery, necessitating sub-millimeter accurac...

A deep learning-informed interpretation of why and when dose metrics outside the PTV can affect the risk of distant metastasis in SBRT NSCLC patients.

Radiation oncology (London, England)
PURPOSE: Recent papers suggested a correlation between the risk of distant metastasis (DM) and dose outside the PTV, though conclusions in different publications conflicted. This study resolves these conflicts and provides a compelling explanation of...

Early experience with an artificial intelligence-based module for brain metastasis detection and segmentation.

Journal of neuro-oncology
INTRODUCTION: - Accurate detection, segmentation, and volumetric analysis of brain lesions are essential in neuro-oncology. Artificial intelligence (AI)-based models have improved the efficiency of these processes. This study evaluated an AI-based mo...