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Risk Assessment

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ToxSTK: A multi-target toxicity assessment utilizing molecular structure and stacking ensemble learning.

Computers in biology and medicine
Drug registration requires risk assessment of new active pharmaceutical ingredients or excipients to ensure they are safe for human health and the environment. However, traditional risk assessment is expensive and relies heavily on animal testing. Ma...

Machine Learning-Based Suicide Risk Prediction Model for Suicidal Trajectory on Social Media Following Suicidal Mentions: Independent Algorithm Validation.

Journal of medical Internet research
BACKGROUND: Previous efforts to apply machine learning-based natural language processing to longitudinally collected social media data have shown promise in predicting suicide risk.

Assessment of urban flood susceptibility based on a novel integrated machine learning method.

Environmental monitoring and assessment
Flood susceptibility assessment is the premise and foundation to prevent flood disaster events effectively. To accurately assess urban flood susceptibility (UFS), this study first analyzes the advantages and disadvantages of multi-layer perceptron (M...

AI-CADR: Artificial Intelligence Based Risk Stratification of Coronary Artery Disease Using Novel Non-Invasive Biomarkers.

IEEE journal of biomedical and health informatics
Coronary artery disease (CAD) is one of the most common causes of sudden cardiac arrest, accounting for a large percentage of global mortality. A timely diagnosis and detection may save a person's life. The research suggests a methodological framewor...

A multimodal machine learning model for the stratification of breast cancer risk.

Nature biomedical engineering
Machine learning models for the diagnosis of breast cancer can facilitate the prediction of cancer risk and subsequent patient management among other clinical tasks. For the models to impact clinical practice, they ought to follow standard workflows,...

Prediction of Brain Cancer Occurrence and Risk Assessment of Brain Hemorrhage Using Hybrid Deep Learning Technique.

Cancer investigation
The prediction of brain cancer occurrence and risk assessment of brain hemorrhage using a hybrid deep learning (DL) technique is a critical area of research in medical imaging analysis. One prominent challenge in this field is the accurate identifica...

Performance of machine learning versus the national early warning score for predicting patient deterioration risk: a single-site study of emergency admissions.

BMJ health & care informatics
OBJECTIVES: Increasing operational pressures on emergency departments (ED) make it imperative to quickly and accurately identify patients requiring urgent clinical intervention. The widespread adoption of electronic health records (EHR) makes rich fe...

Explainable machine learning identifies a polygenic risk score as a key predictor of pancreatic cancer risk in the UK Biobank.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Predicting the risk of developing pancreatic ductal adenocarcinoma (PDAC) is of paramount importance, given its high mortality rate. Current PDAC risk prediction models rely on a limited number of variables, do not include genetics, and h...

Development of machine learning-based models to predict congenital heart disease: A matched case-control study.

International journal of medical informatics
BACKGROUND: The current congenital heart disease (CHD) prediction tools lack adequate interpretability and convenience, hindering the development of personalized CHD management strategies. We developed a machine learning-based risk stratification mod...

Predicting high-flow arteriovenous fistulas and cardiac outcomes in hemodialysis patients.

Journal of vascular surgery
BACKGROUND: Heart failure is common in patients receiving hemodialysis. A high-flow arteriovenous fistula (AVF) may represent a modifiable risk factor for heart failure and death. Currently, no tools exist to assess the risk of developing a high-flow...