AIMC Topic: ROC Curve

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A generalised computer vision model for improved glaucoma screening using fundus images.

Eye (London, England)
IMPORTANCE: Worldwide, glaucoma is a leading cause of irreversible blindness. Timely detection is paramount yet challenging, particularly in resource-limited settings. A novel, computer vision-based model for glaucoma screening using fundus images co...

TPGPred: A Mixed-Feature-Driven Approach for Identifying Thermophilic Proteins Based on GradientBoosting.

International journal of molecular sciences
Thermophilic proteins maintain their stability and functionality under extreme high-temperature conditions, making them of significant importance in both fundamental biological research and biotechnological applications. In this study, we developed a...

Screening the Best Risk Model and Susceptibility SNPs for Chronic Obstructive Pulmonary Disease (COPD) Based on Machine Learning Algorithms.

International journal of chronic obstructive pulmonary disease
BACKGROUND AND PURPOSE: Chronic obstructive pulmonary disease (COPD) is a common and progressive disease that is influenced by both genetic and environmental factors, and genetic factors are important determinants of COPD. This study focuses on scree...

Natural Language Processing of Clinical Documentation to Assess Functional Status in Patients With Heart Failure.

JAMA network open
IMPORTANCE: Serial functional status assessments are critical to heart failure (HF) management but are often described narratively in documentation, limiting their use in quality improvement or patient selection for clinical trials.

Identification and validation of interferon-stimulated gene 15 as a biomarker for dermatomyositis by integrated bioinformatics analysis and machine learning.

Frontiers in immunology
BACKGROUND: Dermatomyositis (DM) is an autoimmune disease that primarily affects the skin and muscles. It can lead to increased mortality, particularly when patients develop associated malignancies or experience fatal complications such as pulmonary ...

Combination of plasma-based lipidomics and machine learning provides a useful diagnostic tool for ovarian cancer.

Journal of pharmaceutical and biomedical analysis
Ovarian cancer (OC), the second leading cause of death among gynecological cancers, is often diagnosed at an advanced stage due to its asymptomatic nature at early stages. This study aimed to explore the diagnostic potential of plasma-based lipidomic...

Cardiac motion correction with a deep learning network for perfusion defect assessment in single-photon emission computed tomography myocardial perfusion imaging.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
BACKGROUND: In myocardial perfusion imaging (MPI) with single-photon emission computed tomography (SPECT), ungated studies are used for evaluation of perfusion defects despite motion blur. We investigate the potential benefit of motion correction usi...

AI derived ECG global longitudinal strain compared to echocardiographic measurements.

Scientific reports
Left ventricular (LV) global longitudinal strain (LVGLS) is versatile; however, it is difficult to obtain. We evaluated the potential of an artificial intelligence (AI)-generated electrocardiography score for LVGLS estimation (ECG-GLS score) to diagn...

A deep learning algorithm that aids visualization of femoral neck fractures and improves physician training.

Injury
PURPOSE: Missed fractures are the most common radiologic error in clinical practice, and erroneous classification could lead to inappropriate treatment and unfavorable prognosis. Here, we developed a fully automated deep learning model to detect and ...

Analysis and validation of diagnostic biomarkers and immune cell infiltration characteristics in Crohn's disease by integrating bioinformatics and machine learning.

Autoimmunity
Crohn's disease (CD) presents significant diagnostic and therapeutic challenges due to its unclear etiology, frequent relapses, and limited treatment options. Traditional monitoring often relies on invasive and costly gastrointestinal procedures. Thi...