AIMC Topic: Saliva

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Assessment of the transmission of live-attenuated chikungunya virus vaccine VLA1553 by Aedes albopictus mosquitoes.

Parasites & vectors
BACKGROUND: Chikungunya virus (CHIKV) is a mosquito-transmitted, arthritogenic alphavirus that causes sporadic outbreaks of often debilitating rheumatic disease. The recently approved CHIKV vaccine, IXCHIQ, is based on a live-attenuated CHIKV strain ...

Standardizing a microbiome pipeline for body fluid identification from complex crime scene stains.

Applied and environmental microbiology
Recent advances in next-generation sequencing have opened up new possibilities for applying the human microbiome in various fields, including forensics. Researchers have capitalized on the site-specific microbial communities found in different parts ...

Investigating handheld near-infrared spectroscopy for forensic body fluid analysis.

Science & justice : journal of the Forensic Science Society
Forensic casework and crime scene examination will often involve the identification and analysis of biological evidence found on a wide variety of surfaces. One type of biological evidence most commonly encountered at the crime scene is body fluids, ...

Exploring non-invasive biomarkers for pulmonary nodule detection based on salivary microbiomics and machine learning algorithms.

Scientific reports
Microorganisms are one of the most promising biomarkers for cancer, and the relationship between microorganisms and lung cancer occurrence and development provides significant potential for pulmonary nodule (PN) diagnosis from a microbiological persp...

Automated Electrical Detection of Proteins for Oral Squamous Cell Carcinoma in an Integrated Microfluidic Chip Using Multi-Frequency Impedance Cytometry and Machine Learning.

Sensors (Basel, Switzerland)
Proteins can act as suitable biomarkers for the prognosis and diagnosis of certain conditions and can help us gain an understanding of the fundamental processes that occur inside an organism. In this work, we present a fully automated machine learnin...

A comparison of different machine learning classifiers in predicting xerostomia and sticky saliva due to head and neck radiotherapy using a multi-objective, multimodal radiomics model.

Biomedical physics & engineering express
. Although radiotherapy techniques are a primary treatment for head and neck cancer (HNC), they are still associated with substantial toxicity and side effects. Machine learning (ML) based radiomics models for predicting toxicity mostly rely on featu...

Multiplex Detection and Quantification of Virus Co-Infections Using Label-free Surface-Enhanced Raman Spectroscopy and Deep Learning Algorithms.

ACS sensors
Multiple respiratory viruses can concurrently or sequentially infect the respiratory tract, making their identification crucial for diagnosis, treatment, and disease management. We present a label-free diagnostic platform integrating surface-enhanced...

Artificial-Intelligence Bio-Inspired Peptide for Salivary Detection of SARS-CoV-2 in Electrochemical Biosensor Integrated with Machine Learning Algorithms.

Biosensors
Developing affordable, rapid, and accurate biosensors is essential for SARS-CoV-2 surveillance and early detection. We created a bio-inspired peptide, using the SAGAPEP AI platform, for COVID-19 salivary diagnostics via a portable electrochemical dev...

Comparative Analysis of Machine Learning Algorithms Used for Translating Aptamer-Antigen Binding Kinetic Profiles to Diagnostic Decisions.

ACS sensors
Current approaches for classifying biosensor data in diagnostics rely on fixed decision thresholds based on receiver operating characteristic (ROC) curves, which can be limited in accuracy for complex and variable signals. To address these limitation...

Precision fetal cardiology detects cyanotic congenital heart disease using maternal saliva metabolome and artificial intelligence.

Scientific reports
Prenatal sonographic diagnosis of congenital heart disease (CHD) can lead to improved morbidity and mortality. However, the diagnostic accuracy of ultrasound, the sole prenatal screening tool, remains limited. Failed prenatal or early newborn detecti...