AIMC Topic: Sensitivity and Specificity

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Quantifying Risk for Anxiety Disorders in Preschool Children: A Machine Learning Approach.

PloS one
Early childhood anxiety disorders are common, impairing, and predictive of anxiety and mood disorders later in childhood. Epidemiological studies over the last decade find that the prevalence of impairing anxiety disorders in preschool children range...

Enhancing analysis throughput, sensitivity and specificity in LC/ESI-MS/MS assay of plasma 25-hydroxyvitamin D by derivatization with triplex 4-(4-dimethylaminophenyl)-1,2,4-triazoline-3,5-dione (DAPTAD) isotopologues.

Journal of pharmaceutical and biomedical analysis
The plasma/serum concentration of 25-hydroxyvitamin D [25(OH)D] is a diagnostic index for vitamin D deficiency/insufficiency, which is associated with a wide range of diseases, such as rickets, cancer and diabetes. We have reported that the derivatiz...

Noninvasive Personalization of a Cardiac Electrophysiology Model From Body Surface Potential Mapping.

IEEE transactions on bio-medical engineering
GOAL: We use noninvasive data (body surface potential mapping, BSPM) to personalize the main parameters of a cardiac electrophysiological (EP) model for predicting the response to different pacing conditions.

Segmentation of Fetal Left Ventricle in Echocardiographic Sequences Based on Dynamic Convolutional Neural Networks.

IEEE transactions on bio-medical engineering
Segmentation of fetal left ventricle (LV) in echocardiographic sequences is important for further quantitative analysis of fetal cardiac function. However, image gross inhomogeneities and fetal random movements make the segmentation a challenging pro...

Lung nodule classification using deep feature fusion in chest radiography.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Lung nodules are small, round, or oval-shaped masses of tissue in the lung region. Early diagnosis and treatment of lung nodules can significantly improve the quality of patients' lives. Because of their small size and the interlaced nature of chest ...

The Variability of Translocator Protein Signal in Brain and Blood of Genotyped Healthy Humans Using In Vivo I-CLINDE SPECT Imaging: A Test-Retest Study.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine
I-CLINDE is a radiotracer developed for SPECT and targets the 18-kDa translocator protein (TSPO). TSPO is upregulated in glial cells and used as a measure of neuroinflammation in a variety of central nervous system diseases. The aim of this study was...

Quantitative EEG Evaluation During Robot-Assisted Foot Movement.

IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society
Passiveand imagined limbmovements induce changes in cerebral oscillatory activity. Central modulatory effects play a role in plastic changes, and are of uttermost importance in rehabilitation. This has extensively been studied for upper limb, but les...

Development of a plasminogen activator inhibitor (PAI-1) assay and comparison of plasma PAI-1 activity in hyperlipidemic/dyslipidemic dogs with either hyperadrenocorticism or diabetes mellitus, and healthy dogs.

Research in veterinary science
Thrombosis is a serious complication of many canine diseases and may be related to decreased fibrinolytic potential. Plasminogen activator inhibitor-1 (PAI-1) is the key regulator of fibrinolysis with increased levels demonstrated in states of pro-th...

An ultrasound image navigation robotic prostate brachytherapy system based on US to MRI deformable image registration method.

Hellenic journal of nuclear medicine
OBJECTIVE: This paper describes an ultrasound image navigation robotic prostate brachytherapy system. It uses a 2D ultrasound (US) probe rigidly fixed to a robotic needle insertion mechanism. Combined with the US probe registration and image registra...

Automatic detection and classification of leukocytes using convolutional neural networks.

Medical & biological engineering & computing
The detection and classification of white blood cells (WBCs, also known as Leukocytes) is a hot issue because of its important applications in disease diagnosis. Nowadays the morphological analysis of blood cells is operated manually by skilled opera...