AIMC Topic: Sensitivity and Specificity

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Automatic Classification on Multi-Modal MRI Data for Diagnosis of the Postural Instability and Gait Difficulty Subtype of Parkinson's Disease.

Journal of Parkinson's disease
BACKGROUND: Patients with the postural instability and gait difficulty subtype (PIGD) of Parkinson's disease (PD) are a refractory challenge in clinical practice. Despite previous attempts that have been made at studying subtype-specific brain altera...

Fractal and twin SVM-based handgrip recognition for healthy subjects and trans-radial amputees using myoelectric signal.

Biomedizinische Technik. Biomedical engineering
Identifying functional handgrip patterns using surface electromygram (sEMG) signal recorded from amputee residual muscle is required for controlling the myoelectric prosthetic hand. In this study, we have computed the signal fractal dimension (FD) an...

Random forests in non-invasive sensorimotor rhythm brain-computer interfaces: a practical and convenient non-linear classifier.

Biomedizinische Technik. Biomedical engineering
There is general agreement in the brain-computer interface (BCI) community that although non-linear classifiers can provide better results in some cases, linear classifiers are preferable. Particularly, as non-linear classifiers often involve a numbe...

Assessing the association between 25-OH vitamin D levels and ROMA score in a population of obese women.

Journal of biological regulators and homeostatic agents
The “Risk of Malignancy Algorithm” (ROMA) combines the diagnostic power of the CA125 and HE4 markers with menopausal status to predict the risk for developing epithelial ovarian cancer (EOC). The aim of this study was to evaluate the association betw...

Interleukin-6 and interleukin-8 in diagnosing neonatal septicemia.

Journal of biological regulators and homeostatic agents
Neonatal septicemia (NS) is a common cause of death of newborn infants, hence early diagnosis and treatment are of the utmost importance. However, lack of specific clinical symptoms and late detection delay a correct diagnosis. It is therefore of gre...

Classifying prostate cancer patients based on total prostate-specific antigen and free prostate-specific antigen features by support vector machine.

Journal of cancer research and therapeutics
AIMS OF STUDY: In this work, we enhanced the role of prostate-specific antigen (PSA) test by examining the relation between free PSA (fPSA) and total PSA (tPSA) value and other biological information such as age and volume of prostate. Our primary go...

Defining a Patient Population With Cirrhosis: An Automated Algorithm With Natural Language Processing.

Journal of clinical gastroenterology
OBJECTIVES: The objective of this study was to use natural language processing (NLP) as a supplement to International Classification of Diseases, Ninth Revision (ICD-9) and laboratory values in an automated algorithm to better define and risk-stratif...

Discrimination of Active and Weakly Active Human BACE1 Inhibitors Using Self-Organizing Map and Support Vector Machine.

Combinatorial chemistry & high throughput screening
β-secretase (BACE1) is an aspartyl protease, which is considered as a novel vital target in Alzheimer`s disease therapy. We collected a data set of 294 BACE1 inhibitors, and built six classification models to discriminate active and weakly active inh...