AIMC Topic: Sepsis

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FedDSS: A data-similarity approach for client selection in horizontal federated learning.

International journal of medical informatics
BACKGROUND AND OBJECTIVE: Federated learning (FL) is an emerging distributed learning framework allowing multiple clients (hospitals, institutions, smart devices, etc.) to collaboratively train a centralized machine learning model without disclosing ...

Machine learning interpretability methods to characterize the importance of hematologic biomarkers in prognosticating patients with suspected infection.

Computers in biology and medicine
OBJECTIVE: To evaluate the effectiveness of Monocyte Distribution Width (MDW) in predicting sepsis outcomes in emergency department (ED) patients compared to other hematologic parameters and vital signs, and to determine whether routine parameters co...

Development and validation of a sepsis risk index supporting early identification of ICU-acquired sepsis: an observational study.

Anaesthesia, critical care & pain medicine
BACKGROUND: Sepsis is a threat to global health, and domestically is the major cause of in-hospital mortality. Due to increases in inpatient morbidity and mortality resulting from sepsis, healthcare providers (HCPs) would accrue significant benefits ...

Transfer learning-enabled outcome prediction for guiding CRRT treatment of the pediatric patients with sepsis.

BMC medical informatics and decision making
Continuous renal replacement therapy (CRRT) is a life-saving procedure for sepsis but the benefit of CRRT varies and prediction of clinical outcomes is valuable in efficient treatment planning. This study aimed to use machine learning (ML) models tra...

Machine learning reveals the rules governing the efficacy of mesenchymal stromal cells in septic preclinical models.

Stem cell research & therapy
BACKGROUND: Mesenchymal Stromal Cells (MSCs) are the preferred candidates for therapeutics as they possess multi-directional differentiation potential, exhibit potent immunomodulatory activity, are anti-inflammatory, and can function like antimicrobi...

Machine learning-based prognostic model for 30-day mortality prediction in Sepsis-3.

BMC medical informatics and decision making
BACKGROUND: Sepsis poses a critical threat to hospitalized patients, particularly those in the Intensive Care Unit (ICU). Rapid identification of Sepsis is crucial for improving survival rates. Machine learning techniques offer advantages over tradit...

Predicting Mortality in Sepsis-Associated Acute Respiratory Distress Syndrome: A Machine Learning Approach Using the MIMIC-III Database.

Journal of intensive care medicine
BackgroundTo develop and validate a mortality prediction model for patients with sepsis-associated Acute Respiratory Distress Syndrome (ARDS).MethodsThis retrospective cohort study included 2466 patients diagnosed with sepsis and ARDS within 24 h of ...

Enhancing Patient Selection in Sepsis Clinical Trials Design Through an AI Enrichment Strategy: Algorithm Development and Validation.

Journal of medical Internet research
BACKGROUND: Sepsis is a heterogeneous syndrome, and enrollment of more homogeneous patients is essential to improve the efficiency of clinical trials. Artificial intelligence (AI) has facilitated the identification of homogeneous subgroups, but how t...

Prediction of sepsis mortality in ICU patients using machine learning methods.

BMC medical informatics and decision making
PROBLEM: Sepsis, a life-threatening condition, accounts for the deaths of millions of people worldwide. Accurate prediction of sepsis outcomes is crucial for effective treatment and management. Previous studies have utilized machine learning for prog...

Distinguishing neonatal culture-negative sepsis from rule-out sepsis with artificial intelligence-derived graphs.

Pediatric research
Novel artificial intelligence methods can aide in identification of cases of conditions using only unstructured electronic health record data. This graph-based method compares comprehensive electronic health records among neonates using temporal data...