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TExCNN: Leveraging Pre-Trained Models to Predict Gene Expression from Genomic Sequences.

Genes
BACKGROUND/OBJECTIVES: Understanding the relationship between DNA sequences and gene expression levels is of significant biological importance. Recent advancements have demonstrated the ability of deep learning to predict gene expression levels direc...

Cyto-Safe: A Machine Learning Tool for Early Identification of Cytotoxic Compounds in Drug Discovery.

Journal of chemical information and modeling
Cytotoxicity is essential in drug discovery, enabling early evaluation of toxic compounds during screenings to minimize toxicological risks. assays support high-throughput screening, allowing for efficient detection of toxic substances while conside...

BUSClean: Open-source software for breast ultrasound image pre-processing and knowledge extraction for medical AI.

PloS one
Development of artificial intelligence (AI) for medical imaging demands curation and cleaning of large-scale clinical datasets comprising hundreds of thousands of images. Some modalities, such as mammography, contain highly standardized imaging. In c...

An explainable deep learning platform for molecular discovery.

Nature protocols
Deep learning approaches have been increasingly applied to the discovery of novel chemical compounds. These predictive approaches can accurately model compounds and increase true discovery rates, but they are typically black box in nature and do not ...

ECLStat: A robust machine learning based visual imaging tool for electrochemiluminescence biosensing.

Computers in biology and medicine
Visual electrochemiluminescence (ECL) has emerged as a prominent diagnostic method for accurately quantifying various disease markers even at point of care setting with high sensitivity and accuracy. It does not employ complicated instruments such as...

Evaluation of RMES, an Automated Software Tool Utilizing AI, for Literature Screening with Reference to Published Systematic Reviews as Case-Studies: Development and Usability Study.

JMIR formative research
BACKGROUND: Systematic reviews and meta-analyses are important to evidence-based medicine, but the information retrieval and literature screening procedures are burdensome tasks. Rapid Medical Evidence Synthesis (RMES; Deloitte Tohmatsu Risk Advisory...

Wound imaging software and digital platform to assist review of surgical wounds using patient smartphones: The development and evaluation of artificial intelligence (WISDOM AI study).

PloS one
INTRODUCTION: Surgical patients frequently experience post-operative complications at home. Digital remote monitoring of surgical wounds via image-based systems has emerged as a promising solution for early detection and intervention. However, the in...

ProPickML: Advancing Clinical Diagnostics with Automated Peak Picking in Label-Free Targeted Proteomics.

Journal of proteome research
In targeted proteomics utilizing Selected Reaction Monitoring (SRM), the precise detection of specific peptides within complex mixtures remains a significant challenge, particularly due to noise and interference in chromatograms. Existing methodologi...