AIMC Topic: Spectrum Analysis, Raman

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Fast screening of COVID-19 inpatient samples by integrating machine learning and label-free SERS methods.

Analytica chimica acta
BACKGROUND: Advances in bio-analyte detection demonstrate the need for innovation to overcome the limitations of traditional methods. Emerging viruses evolve into variants, driving the need for fast screening to minimize the time required for positiv...

A machine learning approach fusing multisource spectral data for prediction of floral origins and taste components of Apis cerana honey.

Food research international (Ottawa, Ont.)
This study explores the use of near-infrared (NIR), mid-infrared (MIR), and Raman spectral fusion for the rapid prediction of floral origins and main taste components in Apis cerana (A. cerana) honey. Feature-level fusion with the partial least squar...

Label-Free Exosomal SERS Detection Assisted by Machine Learning for Accurately Discriminating Cell Cycle Stages and Revealing the Molecular Mechanisms during the Mitotic Process.

Analytical chemistry
Cell cycle analysis is crucial for disease diagnosis and treatment, especially for investigating cell heterogeneity and regulating cell behaviors. Exosomes are highly appealing as noninvasive biomarkers for monitoring real-time changes in the cell cy...

Label-Free Detection of Biochemical Changes during Cortical Organoid Maturation via Raman Spectroscopy and Machine Learning.

Analytical chemistry
Human cerebral organoids have become valuable tools in neurodevelopment research, holding promise for investigating neurological diseases and reducing drug development costs. However, clinical translation and large-scale production of brain organoids...

Neural Network-Enhanced Electrochemical/SERS Dual-Mode Microfluidic Platform for Accurate Detection of Interleukin-6 in Diabetic Wound Exudates.

Analytical chemistry
Interleukin-6 (IL-6) plays a pivotal role in the inflammatory response of diabetic wounds, providing critical insights for clinicians in the development of personalized treatment strategies. However, the low concentration of IL-6 in biological sample...

Towards Rapid and Low-Cost Stroke Detection Using SERS and Machine Learning.

Biosensors
Stroke affects approximately 12 million individuals annually, necessitating swift diagnosis to avert fatal outcomes. Current hospital imaging protocols often delay treatment, underscoring the need for portable diagnostic solutions. We have investigat...

Multi-cancer early detection based on serum surface-enhanced Raman spectroscopy with deep learning: a large-scale case-control study.

BMC medicine
BACKGROUND: Early detection of cancer can help patients with more effective treatments and result in better prognosis. Unfortunately, established cancer screening technologies are limited for use, especially for multi-cancer early detection. In this ...

Rapid detection and quantitative analysis of thiram in fruits using a shape-adaptable flexible SERS substrate combined with deep learning.

Analytical methods : advancing methods and applications
Ensuring food safety necessitates rapid identification of pesticide residues on fruits. Herein, we developed a shape-adaptable flexible surface-enhanced Raman scattering (SERS) substrate, combined with a deep learning algorithm, to quickly detect and...

Neural Network-Assisted Dual-Functional Hydrogel-Based Microfluidic SERS Sensing for Divisional Recognition of Multimolecule Fingerprint.

ACS sensors
To enhance the sensitivity, integration, and practicality of the Raman detection system, a deep learning-based dual-functional subregional microfluidic integrated hydrogel surface-enhanced Raman scattering (SERS) platform is proposed in this paper. F...