The diagnosis of kidney diseases presents significant challenges, including the reliance on variable and unstable biomarkers and the necessity for complex and expensive laboratory tests. Raman spectroscopy emerges as a promising technique for analyzi...
Accurate bacterial identification is vital in medical and healthcare settings. Traditional methods, though reliable, are often time-consuming, underscoring the need for faster, more efficient alternatives. Deep learning-assisted Surface-enhanced Rama...
To enhance the sensitivity, integration, and practicality of the Raman detection system, a deep learning-based dual-functional subregional microfluidic integrated hydrogel surface-enhanced Raman scattering (SERS) platform is proposed in this paper. F...
Rapid and accurate differential diagnosis of infections, sepsis, and septic shock is essential for preventing unnecessary antibiotic overuse and improving the chance of patient survival. To address this, a 3D gold nanogranule decorated gold-silver al...
Amid the increasing global challenge of foodborne diseases, there is an urgent need for rapid and precise pathogen detection methods. This study innovatively integrates surface-enhanced Raman Spectroscopy (SERS) with deep learning technology to devel...
Human and animal health rely on balancing cell division and cell death to maintain normal homeostasis. This process is accomplished by regulated cell death (RCD), whose imbalance can lead to disease. Currently, the most frequently used method for ana...
Large language models (LLMs) hold significant promise in the field of medical diagnosis. There are still many challenges in the direct diagnosis of hepatocellular carcinoma (HCC). α-Fetoprotein (AFP) is a commonly used tumor marker for liver cancer. ...
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
39929115
Accurate therapeutic drug monitoring (TDM) of antibiotics including ceftriaxone, ampicillin, and vancomycin plays an important role in the treatment of neonatal sepsis, a common and life-threatening disease in neonates. A highly sensitive surface-enh...
Proceedings of the National Academy of Sciences of the United States of America
39928861
The detection and identification of polycyclic aromatic hydrocarbons (PAHs) and their derivatives, polycyclic aromatic compounds (PACs), are essential for environmental and health monitoring, for assessing toxicological exposure and their associated ...
Analytical methods : advancing methods and applications
39925033
Ensuring food safety necessitates rapid identification of pesticide residues on fruits. Herein, we developed a shape-adaptable flexible surface-enhanced Raman scattering (SERS) substrate, combined with a deep learning algorithm, to quickly detect and...