Sputum

Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to Be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort.

The Journal of molecular diagnostics : JMD 29269279

Tuberculosis (TB) diagnosis among sputum-scarce patients is time consuming. Thus, a nonsputum diagnostic alternative is urgently needed. The Mycobacterium tuberculosis-specific transrenal (Tr) DNA from urine is a potential target for TB diagnostics. ...

Adult Aged Aged, 80 and over Biomarkers Cohort Studies Cross-Sectional Studies Diagnostic Tests, Routine DNA, Bacterial Female HIV Infections Humans Logistic Models Male Microscopy Middle Aged Molecular Diagnostic Techniques Multivariate Analysis Mycobacterium tuberculosis Point-of-Care Systems Polymerase Chain Reaction Risk Factors Sensitivity and Specificity South Africa Sputum Tuberculosis, Pulmonary Universities Young Adult

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Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads.

International journal of mycobacteriology 27649873

BACKGROUND: A concentration of specimen is recommended for the effective recovery of Mycobacterium tuberculosis (MTB), but the bacteriological efficiency is not well evaluated. The present study evaluated the factors contributing to concentration eff...

Analysis of Variance Bacteriological Techniques Centrifugation Humans Immunomagnetic Separation Japan Mycobacterium tuberculosis Sensitivity and Specificity Specimen Handling Sputum Tuberculosis, Pulmonary

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Tuberculous Pericarditis is Multibacillary and Bacterial Burden Drives High Mortality.

EBioMedicine 26870789

BACKGROUND: Tuberculous pericarditis is considered to be a paucibacillary process; the large pericardial fluid accumulation is attributed to an inflammatory response to tuberculoproteins. Mortality rates are high. We investigated the role of clinical...

Adult Aged Antitubercular Agents Artificial Intelligence Bacterial Load CD4 Lymphocyte Count Comorbidity Female Follow-Up Studies Humans Logistic Models Male Middle Aged Mycobacterium tuberculosis Pericardial Effusion Pericarditis, Tuberculous Registries Sputum Young Adult

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Unsupervised learning technique identifies bronchiectasis phenotypes with distinct clinical characteristics.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 27046724

BACKGROUND: Unsupervised learning technique allows researchers to identify different phenotypes of diseases with complex manifestations.

Adult Aged Anti-Bacterial Agents Body Mass Index Bronchiectasis Cluster Analysis Cohort Studies Cough Female Follow-Up Studies Forced Expiratory Volume Humans Male Middle Aged Phenotype Prospective Studies Pseudomonas aeruginosa Quality of Life Risk Factors Sputum Unsupervised Machine Learning

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Qualitative analysis of biological tuberculosis samples by an electronic nose-based artificial neural network.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 28633707

OBJECTIVE: To apply an e-nose system for monitoring headspace volatiles in biological samples from Egyptian patients with active pulmonary tuberculosis (TB) and healthy controls (HCs) and compare them with standard sputum analysis.

Adolescent Adult Aged Case-Control Studies Egypt Electronic Nose Female Humans Male Mass Screening Middle Aged Neural Networks, Computer Principal Component Analysis Sensitivity and Specificity Socioeconomic Factors Sputum Tuberculosis, Pulmonary Young Adult

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Classification of Sputum Sounds Using Artificial Neural Network and Wavelet Transform.

International journal of biological sciences 29989104

Sputum sounds are biological signals used to evaluate the condition of sputum deposition in a respiratory system. To improve the efficiency of intensive care unit (ICU) staff and achieve timely clearance of secretion in patients with mechanical venti...

Algorithms Humans Neural Networks, Computer Respiratory System Sputum Wavelet Analysis

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Screening for active pulmonary tuberculosis: Development and applicability of artificial neural network models.

Tuberculosis (Edinburgh, Scotland) 30029922

Tuberculosis (TB) remains a significant public health challenge, motivated by the diversity of healthcare epidemiological settings, as other factors. Cost-effective screening has substantial importance for TB control, demanding new diagnostic tools. ...

Adult Bacteriological Techniques Brazil Databases, Factual Decision Support Systems, Clinical Decision Support Techniques Diagnosis, Computer-Assisted Female Humans Lung Male Mass Screening Middle Aged Mycobacterium tuberculosis Neural Networks, Computer Predictive Value of Tests Prevalence Reproducibility of Results Risk Assessment Risk Factors Sputum Tuberculosis, Pulmonary Young Adult

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Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 30496461

BACKGROUND: Levofloxacin is used for the treatment of multidrug-resistant tuberculosis; however the optimal dose is unknown.

Algorithms Antitubercular Agents Artificial Intelligence Drug Resistance, Multiple, Bacterial Drug Therapy, Combination Humans Levofloxacin Microbial Sensitivity Tests Monte Carlo Method Mycobacterium tuberculosis Sputum Tuberculosis, Multidrug-Resistant Tuberculosis, Pulmonary

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An effective and accurate identification system of Mycobacterium tuberculosis using convolution neural networks.

Microscopy research and technique 30741460

Tuberculosis (TB) remains the leading cause of morbidity and mortality from infectious disease in developing countries. The sputum smear microscopy remains the primary diagnostic laboratory test. However, microscopic examination is always time-consum...

Humans Image Processing, Computer-Assisted Microscopy Mycobacterium tuberculosis Neural Networks, Computer Sputum Tuberculosis, Pulmonary

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Comparison of Xpert MTB/RIF (G4) and Xpert Ultra, including trace readouts, for the diagnosis of pulmonary tuberculosis in a TB and HIV endemic setting.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 32247825

BACKGROUND: There are limited data about Xpert-Ultra performance in different settings, in HIV-infected persons, in those with a history of previous TB, and with trace readouts.

Adult Aged Expert Systems Female HIV Infections Humans Limit of Detection Male Middle Aged Mycobacterium tuberculosis Real-Time Polymerase Chain Reaction Sensitivity and Specificity Sputum Tuberculosis, Pulmonary Young Adult

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Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to Be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort.

Factors contribute to efficiency of specimen concentration of Mycobacterium tuberculosis by centrifugation and magnetic beads.

Tuberculous Pericarditis is Multibacillary and Bacterial Burden Drives High Mortality.

Unsupervised learning technique identifies bronchiectasis phenotypes with distinct clinical characteristics.

Qualitative analysis of biological tuberculosis samples by an electronic nose-based artificial neural network.

Classification of Sputum Sounds Using Artificial Neural Network and Wavelet Transform.

Screening for active pulmonary tuberculosis: Development and applicability of artificial neural network models.

Levofloxacin Pharmacokinetics/Pharmacodynamics, Dosing, Susceptibility Breakpoints, and Artificial Intelligence in the Treatment of Multidrug-resistant Tuberculosis.

An effective and accurate identification system of Mycobacterium tuberculosis using convolution neural networks.

Comparison of Xpert MTB/RIF (G4) and Xpert Ultra, including trace readouts, for the diagnosis of pulmonary tuberculosis in a TB and HIV endemic setting.

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