AIMC Topic: Tissue Engineering

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Machine Learning-Guided Three-Dimensional Printing of Tissue Engineering Scaffolds.

Tissue engineering. Part A
Various material compositions have been successfully used in 3D printing with promising applications as scaffolds in tissue engineering. However, identifying suitable printing conditions for new materials requires extensive experimentation in a time ...

Machine learning to predict mesenchymal stem cell efficacy for cartilage repair.

PLoS computational biology
Inconsistent therapeutic efficacy of mesenchymal stem cells (MSCs) in regenerative medicine has been documented in many clinical trials. Precise prediction on the therapeutic outcome of a MSC therapy based on the patient's conditions would provide va...

A Coupled FEM-SPH Modeling Technique to Investigate the Contractility of Biohybrid Thin Films.

Advanced biosystems
Biohybrid actuators have the potential to overcome the limitations of traditional actuators employed in robotics, thanks to the unique features of living contractile muscle cells, which can be used to power artificial elements. This paper describes a...

Improving patient outcomes with regenerative medicine: How the Regenerative Medicine Manufacturing Society plans to move the needle forward in cell manufacturing, standards, 3D bioprinting, artificial intelligence-enabled automation, education, and training.

Stem cells translational medicine
The Regenerative Medicine Manufacturing Society (RMMS) is the first and only professional society dedicated toward advancing manufacturing solutions for the field of regenerative medicine. RMMS's vision is to provide greater patient access to regener...

Bioinspired Soft Robot with Incorporated Microelectrodes.

Journal of visualized experiments : JoVE
Bioinspired soft robotic systems that mimic living organisms using engineered muscle tissue and biomaterials are revolutionizing the current biorobotics paradigm, especially in biomedical research. Recreating artificial life-like actuation dynamics i...

A New Era for Cyborg Science Is Emerging: The Promise of Cyborganic Beings.

Advanced healthcare materials
Living flesh, hacked beyond known biological borders, and sophisticated machineries, made by humans, are currently being united to address some of the impending challenges in medicine. Imagine biological systems made from smart biomaterials with the ...

Applications of Computer Modeling and Simulation in Cartilage Tissue Engineering.

Tissue engineering and regenerative medicine
BACKGROUND: Advances in cartilage tissue engineering have demonstrated noteworthy potential for developing cartilage for implantation onto sites impacted by joint degeneration and injury. To supplement resource-intensive in vivo and in vitro studies ...

Improving the Rate of Translation of Tissue Engineering Products.

Advanced healthcare materials
Over 100 000 research articles and 9000 patents have been published on tissue engineering (TE) in the past 20 years. Yet, very few TE products have made their way to the market during the same period. Experts have proposed a variety of strategies to ...

A Remotely Controlled Transformable Soft Robot Based on Engineered Cardiac Tissue Construct.

Small (Weinheim an der Bergstrasse, Germany)
Many living organisms undergo conspicuous or abrupt changes in body structure, which is often accompanied by a behavioral change. Inspired by the natural metamorphosis, robotic systems can be designed as reconfigurable to be multifunctional. Here, a ...

Acquisition and reconstruction of 4D surfaces of axolotl embryos with the flipping stage robotic microscope.

Bio Systems
We have designed and constructed a Flipping Stage for a light microscope that can view the whole exterior surface of a 2 mm diameter developing axolotl salamander embryo. It works by rapidly inverting the bottom-heavy embryo, imaging it as it rights ...