AIMC Topic: Tissue Scaffolds

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Rapid prediction of lab-grown tissue properties using deep learning.

Physical biology Oct 19, 2023
The interactions between cells and the extracellular matrix are vital for the self-organisation of tissues. In this paper we present proof-of-concept to use machine learning tools to predict the role of this mechanobiology in the self-organisation of...
Neural Networks, Computer Extracellular Matrix Tissue Engineering Tissue Scaffolds Machine Learning Deep Learning Hydrogels
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Automatic Photo-Cross-Linking System for Robotic-Based In Situ Bioprinting.

ACS biomaterials science & engineering Oct 12, 2023
This work reports the design and validation of an innovative automatic photo-cross-linking device for robotic-based in situ bioprinting. Photo-cross-linking is the most promising polymerization technique when considering biomaterial deposition direct...
Tissue Scaffolds Gelatin Robotic Surgical Procedures Bioprinting Tissue Engineering Humans Printing, Three-Dimensional Robotics
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Advanced Soft Robotic System for In Situ 3D Bioprinting and Endoscopic Surgery.

Advanced science (Weinheim, Baden-Wurttemberg, Germany) Feb 19, 2023
Three-dimensional (3D) bioprinting technology offers great potential in the treatment of tissue and organ damage. Conventional approaches generally rely on a large form factor desktop bioprinter to create in vitro 3D living constructs before introduc...
Bioprinting Swine Robotics Tissue Engineering Biocompatible Materials Tissue Scaffolds Animals
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Robot-assisted in situ bioprinting of gelatin methacrylate hydrogels with stem cells induces hair follicle-inclusive skin regeneration.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie Dec 17, 2022
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed...
Humans Robotics Stem Cells Methacrylates Tissue Engineering Tissue Scaffolds Hydrogels Biocompatible Materials Bioprinting Hair Follicle Gelatin
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Compensating the cell-induced light scattering effect in light-based bioprinting using deep learning.

Biofabrication Dec 3, 2021
Digital light processing (DLP)-based three-dimensional (3D) printing technology has the advantages of speed and precision comparing with other 3D printing technologies like extrusion-based 3D printing. Therefore, it is a promising biomaterial fabrica...
Bioprinting Tissue Engineering Tissue Scaffolds Deep Learning Printing, Three-Dimensional Biocompatible Materials
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Stereotactic technology for 3D bioprinting: from the perspective of robot mechanism.

Biofabrication Aug 13, 2021
Three-dimensional (3D) bioprinting has been widely applied in the field of biomedical engineering because of its rapidly individualized fabrication and precisely geometric designability. The emerging demand for bioprinted tissues/organs with bio-insp...
Bioprinting Tissue Engineering Tissue Scaffolds Technology Printing, Three-Dimensional Robotics
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Integrated functional neuronal network analysis of 3D silk-collagen scaffold-based mouse cortical culture.

STAR protocols Jan 25, 2021
Bioengineered 3D tunable neuronal constructs are a versatile platform for studying neuronal network functions, offering numerous advantages over existing technologies and providing for the discovery of new biological insights. Functional neural netwo...
Cell Culture Techniques Nerve Net Cell Differentiation Silk Neurons Neural Networks, Computer Collagen Animals Tissue Scaffolds Mice Cerebral Cortex
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The 3D reconstructed skin micronucleus assay using imaging flow cytometry and deep learning: A proof-of-principle investigation.

Mutation research. Genetic toxicology and environmental mutagenesis Jan 20, 2021
The reconstructed skin micronucleus (RSMN) assay was developed in 2006, as an in vitro alternative for genotoxicity evaluation of dermally applied chemicals or products. In the years since, significant progress has been made in the optimization of th...
Feasibility Studies Humans Models, Biological Artificial Intelligence Mutagenicity Tests Automation, Laboratory False Positive Reactions Software Predictive Value of Tests Tissue Scaffolds Mitomycin Deep Learning Proof of Concept Study Flow Cytometry Skin, Artificial Image Processing, Computer-Assisted Micronucleus Tests Skin
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Machine Learning-Guided Three-Dimensional Printing of Tissue Engineering Scaffolds.

Tissue engineering. Part A Oct 15, 2020
Various material compositions have been successfully used in 3D printing with promising applications as scaffolds in tissue engineering. However, identifying suitable printing conditions for new materials requires extensive experimentation in a time ...
Machine Learning Printing, Three-Dimensional Porosity Tissue Engineering Tissue Scaffolds
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Bioinspired Soft Robot with Incorporated Microelectrodes.

Journal of visualized experiments : JoVE Feb 28, 2020
Bioinspired soft robotic systems that mimic living organisms using engineered muscle tissue and biomaterials are revolutionizing the current biorobotics paradigm, especially in biomedical research. Recreating artificial life-like actuation dynamics i...
Myocardial Contraction Tissue Engineering Polyethylene Glycols Rats, Sprague-Dawley Tissue Scaffolds Animals Hydrogels Robotics Microelectrodes Biocompatible Materials Rats Biomimetics Myocardium Nanotubes, Carbon Myocytes, Cardiac
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