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Tumor Cells, Cultured

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Albumin binding, anticancer and antibacterial properties of synthesized zero valent iron nanoparticles.

International journal of nanomedicine
BACKGROUND: Nanoparticles (NPs) have been emerging as potential players in modern medicine with clinical applications ranging from therapeutic purposes to antimicrobial agents. However, before applications in medical agents, some in vitro studies sho...

Investigation of serum Ki-67 as a biomarker in tumor-bearing dogs.

Research in veterinary science
Because of the limited number of tumor markers in veterinary medicine, there is need for identifying new markers. Ki-67 has been investigated as a tissue marker of malignant alterations. We hypothesized that Ki-67 would also be measurable in serum an...

Anticancer and anti-inflammatory activities of girinimbine isolated from .

Drug design, development and therapy
Therapy that directly targets apoptosis and/or inflammation could be highly effective for the treatment of cancer. is an edible herb that has been traditionally used for cancer treatment as well as inflammation. Here, we describe that girinimbine, a...

Regulation of demethylation and re-expression of RASSF1A gene in hepatocellular carcinoma cell lines treated with NCTD in vitro.

Journal of cancer research and therapeutics
BACKGROUND: Hepatocellular carcinoma, a lethal malignant neoplasm with poor prognosis, has dismal results of surgical resection and chemoradiotherapy. Norcantharidin (NCTD), the demethylated analog of cantharidin derived from a traditional Chinese me...

Magnetically driven microrobotic system for cancer cell manipulation.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Lab-on-a-chip applications, such as single cell manipulation and targeted delivery of chemicals, could greatly benefit from mobile untethered microdevices able to move in fluidic environments by using magnetic fields. In this paper a magnetically dri...

Detection and Recognition for Life State of Cell Cancer Using Two-Stage Cascade CNNs.

IEEE/ACM transactions on computational biology and bioinformatics
Cancer cell detection and its stages recognition of life cycle are an important step to analyze cellular dynamics in the automation of cell based-experiments. In this work, a two-stage hierarchical method is proposed to detect and recognize different...

Assessing microscope image focus quality with deep learning.

BMC bioinformatics
BACKGROUND: Large image datasets acquired on automated microscopes typically have some fraction of low quality, out-of-focus images, despite the use of hardware autofocus systems. Identification of these images using automated image analysis with hig...

Deep transfer learning-based hologram classification for molecular diagnostics.

Scientific reports
Lens-free digital in-line holography (LDIH) is a promising microscopic tool that overcomes several drawbacks (e.g., limited field of view) of traditional lens-based microcopy. However, extensive computation is required to reconstruct object images fr...