AIMC Topic: United Kingdom

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Machine learning and clinician predictions of antibiotic resistance in Enterobacterales bloodstream infections.

The Journal of infection
BACKGROUND: Patients with Gram-negative bloodstream infections are at risk of serious adverse outcomes without active treatment, but identifying who has antimicrobial resistance (AMR) to target empirical treatment is challenging.

Development of an individualized dementia risk prediction model using deep learning survival analysis incorporating genetic and environmental factors.

Alzheimer's research & therapy
BACKGROUND: Dementia is a major public health challenge in modern society. Early detection of high-risk dementia patients and timely intervention or treatment are of significant clinical importance. Neural network survival analysis represents the mos...

Automated redaction of names in adverse event reports using transformer-based neural networks.

BMC medical informatics and decision making
BACKGROUND: Automated recognition and redaction of personal identifiers in free text can enable organisations to share data while protecting privacy. This is important in the context of pharmacovigilance since relevant detailed information on the cli...

Evaluation of a machine learning-based metabolic marker for coronary artery disease in the UK Biobank.

Atherosclerosis
BACKGROUND AND AIMS: An in silico quantitative score of coronary artery disease (ISCAD), built using machine learning and clinical data from electronic health records, has been shown to result in gradations of risk of subclinical atherosclerosis, cor...

Interpretable deep learning survival predictions in sporadic Creutzfeldt-Jakob disease.

Journal of neurology
BACKGROUND: Sporadic Creutzfeldt-Jakob disease (sCJD) is a rapidly progressive and fatal prion disease with significant public health implications. Survival is heterogenous, posing challenges for prognostication and care planning. We developed a surv...

Performance of machine learning versus the national early warning score for predicting patient deterioration risk: a single-site study of emergency admissions.

BMJ health & care informatics
OBJECTIVES: Increasing operational pressures on emergency departments (ED) make it imperative to quickly and accurately identify patients requiring urgent clinical intervention. The widespread adoption of electronic health records (EHR) makes rich fe...

Explainable machine learning identifies a polygenic risk score as a key predictor of pancreatic cancer risk in the UK Biobank.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Predicting the risk of developing pancreatic ductal adenocarcinoma (PDAC) is of paramount importance, given its high mortality rate. Current PDAC risk prediction models rely on a limited number of variables, do not include genetics, and h...

Enhancements in artificial intelligence for medical examinations: A leap from ChatGPT 3.5 to ChatGPT 4.0 in the FRCS trauma & orthopaedics examination.

The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
INTRODUCTION: ChatGPT is a sophisticated AI model capable of generating human-like text based on the input it receives. ChatGPT 3.5 showed an inability to pass the FRCS (Tr&Orth) examination due to a lack of higher-order judgement in previous studies...

Natural language processing data services for healthcare providers.

BMC medical informatics and decision making
PURPOSE OF REVIEW: Embedding machine learning workflows into real-world hospital environments is essential to ensure model alignment with clinical workflows and real-world data. Many non-healthcare industries undergoing digital transformation have al...