Computational and mathematical methods in medicine
May 18, 2015
Ultrasound examination (US) does a key role in the diagnosis and management of the patients with clinically suspected appendicitis which is the most common abdominal surgical emergency. Among the various sonographic findings of appendicitis, outer di...
Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
May 6, 2015
PURPOSE: Adaptive radiation therapy (ART) is an advanced field of radiation oncology. Image-guided radiation therapy (IGRT) methods can support daily setup and assess anatomical variations during therapy, which could prevent incorrect dose distributi...
OBJECTIVE: The paper addresses the problem of automatic detection of basal cell carcinoma (BCC) in histopathology images. In particular, it proposes a framework to both, learn the image representation in an unsupervised way and visualize discriminati...
Journal of the American Medical Informatics Association : JAMIA
Apr 9, 2015
OBJECTIVE: Extracting medical knowledge from electronic medical records requires automated approaches to combat scalability limitations and selection biases. However, existing machine learning approaches are often regarded by clinicians as black boxe...
Computer methods and programs in biomedicine
Mar 18, 2015
Gene expression data analysis is based on the assumption that co-expressed genes imply co-regulated genes. This assumption is being reformulated because the co-expression of a group of genes may be the result of an independent activation with respect...
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and ultimately fatal neurodegenerative disease, caused by the loss of motor neurons in the brain and spinal cord. Although 10% of ALS cases are familial (FALS), the majority are sporadic (S...
Gene expression patterns are determined to a large extent by transcription factor (TF) binding to noncoding regulatory regions in the genome. However, gene expression cannot yet be systematically predicted from genome sequences, in part because nonfu...
BACKGROUND: Patient-specific quality assurance (PSQA) is essential to guarantee the requested accuracy and safety of high-precision radiotherapy treatments. With the widespread adoption of modulated-intensity techniques, there is a growing need for i...
Cell therapies like Chimeric Antigen Receptor (CAR)-T cell therapy deliver living cells to patients as active pharmaceutical ingredients. Manufacturing of these cells is complex, often yielding, heterogeneous products and high failure rates. Quality ...
Join thousands of healthcare professionals staying informed about the latest AI breakthroughs in medicine. Get curated insights delivered to your inbox.