AIMC Topic: Wound Healing

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Clinically validated classification of chronic wounds method with memristor-based cellular neural network.

Scientific reports
Chronic wounds are a syndrome that affects around 4% of the world population due to several pathologies. The COV-19 pandemic has enforced the need of developing new techniques and technologies that can help clinicians to monitor the affected patients...

A programmable, open-source robot that scratches cultured tissues to investigate cell migration, healing, and tissue sculpting.

Cell reports methods
Despite the widespread popularity of the "scratch assay," where a pipette is dragged manually through cultured tissue to create a gap to study cell migration and healing, it carries significant drawbacks. Its heavy reliance on manual technique can co...

Large Scale Ultrafast Manufacturing of Wireless Soft Bioelectronics Enabled by Autonomous Robot Arm Printing Assisted by a Computer Vision-Enabled Guidance System for Personalized Wound Healing.

Advanced healthcare materials
A Customized wound patch for Advanced tissue Regeneration with Electric field (CARE), featuring an autonomous robot arm printing system guided by a computer vision-enabled guidance system for fast image recognition is introduced. CARE addresses the g...

Machine learning accelerates the discovery of epitope-based dual-bioactive peptides against skin infections.

International journal of antimicrobial agents
OBJECTIVES: Skin injuries and infections are an inevitable part of daily human life, particularly with chronic wounds, becoming an increasing socioeconomic burden. In treating skin infections and promoting wound healing, bioactive peptides may hold s...

Deep learning reveals a damage signalling hierarchy that coordinates different cell behaviours driving wound re-epithelialisation.

Development (Cambridge, England)
One of the key tissue movements driving closure of a wound is re-epithelialisation. Earlier wound healing studies describe the dynamic cell behaviours that contribute to wound re-epithelialisation, including cell division, cell shape changes and cell...

Deep learning for rapid analysis of cell divisions in vivo during epithelial morphogenesis and repair.

eLife
Cell division is fundamental to all healthy tissue growth, as well as being rate-limiting in the tissue repair response to wounding and during cancer progression. However, the role that cell divisions play in tissue growth is a collective one, requir...

Using deep learning for predicting the dynamic evolution of breast cancer migration.

Computers in biology and medicine
BACKGROUND: Breast cancer (BC) remains a prevalent health concern, with metastasis as the main driver of mortality. A detailed understanding of metastatic processes, particularly cell migration, is fundamental to improve therapeutic strategies. The w...

The impact of machine learning on the prediction of diabetic foot ulcers - A systematic review.

Journal of tissue viability
INTRODUCTION: Globally, diabetes mellitus poses a significant health challenge as well as the associated complications of diabetes, such as diabetic foot ulcers (DFUs). The early detection of DFUs is important in the healing process and machine learn...

An automated in vitro wound healing microscopy image analysis approach utilizing U-net-based deep learning methodology.

BMC medical imaging
BACKGROUND: The assessment of in vitro wound healing images is critical for determining the efficacy of the therapy-of-interest that may influence the wound healing process. Existing methods suffer significant limitations, such as user dependency, ti...