AI Medical Compendium Journal:
Cell reports. Medicine

Showing 1 to 10 of 51 articles

MMRNet: Ensemble deep learning models for predicting mismatch repair deficiency in endometrial cancer from histopathological images.

Cell reports. Medicine
Combining molecular classification with clinicopathologic methods improves risk assessment and chooses therapies for endometrial cancer (EC). Detecting mismatch repair (MMR) deficiencies in EC is crucial for screening Lynch syndrome and identifying i...

MetaGP: A generative foundation model integrating electronic health records and multimodal imaging for addressing unmet clinical needs.

Cell reports. Medicine
Artificial intelligence makes strides in specialized diagnostics but faces challenges in complex clinical scenarios, such as rare disease diagnosis and emergency condition identification. To address these limitations, we develop Meta General Practiti...

A CT-based deep learning-driven tool for automatic liver tumor detection and delineation in patients with cancer.

Cell reports. Medicine
Liver tumors, whether primary or metastatic, significantly impact the outcomes of patients with cancer. Accurate identification and quantification are crucial for effective patient management, including precise diagnosis, prognosis, and therapy evalu...

Assessments of lung nodules by an artificial intelligence chatbot using longitudinal CT images.

Cell reports. Medicine
Large language models have shown efficacy across multiple medical tasks. However, their value in the assessment of longitudinal follow-up computed tomography (CT) images of patients with lung nodules is unclear. In this study, we evaluate the ability...

Multimodal integration using a machine learning approach facilitates risk stratification in HR+/HER2- breast cancer.

Cell reports. Medicine
Hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer is the most common type of breast cancer, with continuous recurrence remaining an important clinical issue. Current relapse predictive models in H...

Enhancing AI reliability: A foundation model with uncertainty estimation for optical coherence tomography-based retinal disease diagnosis.

Cell reports. Medicine
Inability to express the confidence level and detect unseen disease classes limits the clinical implementation of artificial intelligence in the real world. We develop a foundation model with uncertainty estimation (FMUE) to detect 16 retinal conditi...

Interpretable multi-modal artificial intelligence model for predicting gastric cancer response to neoadjuvant chemotherapy.

Cell reports. Medicine
Neoadjuvant chemotherapy assessment is imperative for prognostication and clinical management of locally advanced gastric cancer. We propose an incremental supervised contrastive learning model (iSCLM), an interpretable artificial intelligence framew...

Development and validation of a machine learning model to predict myocardial blood flow and clinical outcomes from patients' electrocardiograms.

Cell reports. Medicine
We develop a machine learning (ML) model using electrocardiography (ECG) to predict myocardial blood flow reserve (MFR) and assess its prognostic value for major adverse cardiovascular events (MACEs). Using 3,639 ECG-positron emission tomography (PET...

Reconstruction of patient-specific confounders in AI-based radiologic image interpretation using generative pretraining.

Cell reports. Medicine
Reliably detecting potentially misleading patterns in automated diagnostic assistance systems, such as those powered by artificial intelligence (AI), is crucial for instilling user trust and ensuring reliability. Current techniques fall short in visu...

Unraveling the impact of therapeutic drug monitoring via machine learning for patients with sepsis.

Cell reports. Medicine
Clinical studies investigating the benefits of beta-lactam therapeutic drug monitoring (TDM) among critically ill patients are hindered by small patient groups, variability between studies, patient heterogeneity, and inadequate use of TDM. Accordingl...