SIGNIFICANCE: Molecular photoacoustic (PA) imaging with exogenous dyes faces a significant challenge due to the photobleaching of the dye that can compromise tissue visualization, particularly in 3D imaging. Addressing this limitation can revolutioni...
SIGNIFICANCE: Diffuse correlation tomography (DCT) is an emerging technique for the noninvasive measurement of breast microvascular blood flow, whereas its capability to categorize benign and malignant breast lesions has not been extensively validate...
SIGNIFICANCE: Automated segmentation of periarterial and perivenous capillary-free zones (CFZs) in optical coherence tomography angiography (OCTA) can significantly improve early detection and monitoring of diabetic retinopathy (DR), a leading cause ...
SIGNIFICANCE: Stroke is a leading cause of disability worldwide, necessitating rapid and accurate diagnosis to limit irreversible brain damage. However, many advanced imaging modalities (computerized tomography, magnetic resonance imaging) remain ina...
SIGNIFICANCE: Spatial frequency domain imaging (SFDI) is an emerging optical imaging modality for visualizing tissue absorption and scattering properties. This approach is promising for noninvasive wide field-of-view (FOV) monitoring of biophysiologi...
SIGNIFICANCE: Investigating optical properties (OPs) is crucial in the field of biophotonics, as it has a broad impact on understanding light-tissue interactions. However, current techniques, such as inverse Monte Carlo simulations (IMCS), have limit...
SIGNIFICANCE: High-resolution optical imaging at significant depths is challenging due to scattering, which impairs image quality in living matter with complex structures. We address the need for improved imaging techniques in deep tissues.
SIGNIFICANCE: Alcohol consumption monitoring is essential for forensic and healthcare applications. While breath and blood alcohol concentration sensors are currently the most common methods, there is a growing need for faster, non-invasive, and more...
SIGNIFICANCE: The incidence of keratinocyte carcinomas (KCs) is increasing every year, making the task of developing new methods for KC early diagnosis of utmost medical and economical importance.
SIGNIFICANCE: Current methods for complex conjugate removal (CCR) in frequency-domain optical coherence tomography (FD-OCT) often require additional hardware components, which increase system complexity and cost. A software-based solution would provi...